Mariners-White Sox 4/13 Prediction, Pitchers & Betting Tips

Eddie Griffin

In his season opener, last year’s AL Cy Young Award winner got off to a winning start with his new team, as Robbie Ray pitched the Seattle Mariners to a win over the Minnesota Twins. This evening, Ray will get the ball as the Mariners look to even up their MLB series with the Chicago White Sox.

After edging the Twins 2-1 to open the season behind seven strong innings from Ray, the M’s won a second straight one-run game in Minneapolis. They have yet to win again, having lost the last two of their series with the Twins and then falling in yesterday’s opener in Chicago.

The White Sox, who eked out a 3-2 win on Tuesday, have opened their AL Central title defense with three wins in four games and already sit atop the division standings.

Preseason MLB division odds placed the South Siders as the biggest favorite in any of the six divisions, and it looks like it will take a lot for the Cleveland Guardians, Detroit Tigers, Kansas City Royals, or Minnesota Twins to knock the White Sox off of their perch in the AL Central.

Seattle Mariners vs. Chicago White Sox April 13 MLB Betting Odds, Starting Pitchers, and Matchup Information

Matchup Information

  • Game Matchup: Seattle Mariners (2-3, t-3rd in the AL West) vs. Chicago White Sox (3-1, 1st in the AL Central)
  • Venue & Location: U.S. Cellular Field (Chicago, Illinois)
  • Date: Wednesday, April 13, 2022
  • Time: 7:10 p.m. ET
  • How to Watch Mariners vs. White Sox: MLB Network (national), Root Sports Northwest (Mariners), NBC Sports Chicago (White S9x)

Mariners vs. White Sox April 13 Starting Pitching Matchup

  • Seattle Mariners: Robbie Ray (2022: 1-0, 1.29 ERA)
  • Chicago White Sox: Dallas Keuchel (first start in 2022 – 9-9, 5.28 ERA in 32 appearances in 2021)

Mariners vs. White Sox April 13 Betting Odds

FanDuel Sportsbook

  • Moneyline: Seattle Mariners +102, Chicago White Sox -120
  • Total: OVER 9 (-102), UNDER 9 (-120)
  • Run Line: Seattle Mariners +1.5 (-205), Chicago White Sox -1.5 (+168)

Caesars Sportsbook

  • Moneyline: Seattle Mariners +100, Chicago White Sox -120
  • Total: OVER 9 (-105), UNDER 9 (-115)
  • Run Line: Seattle Mariners +1.5 (-190), Chicago White Sox -1.5 (+160)


  • Moneyline: Seattle Mariners +105, Chicago White Sox -121
  • Total: OVER 9 (-105), UNDER 9 (-117)
  • Run Line: Seattle Mariners -1.5 (+165), Chicago White Sox +1.5 (-210)

Seattle Mariners vs. Chicago White Sox April 13 Prediction and Best Bets

Prediction: Seattle to win

Best Bets: Mariners ML (+105 at BetRivers) & UNDER 9 (-115 at Caesars Sportsbook)

The only White Sox hitters who have had double-digit at-bats against Ray are Yasmani Grandal (3 for 13) and Josh Harrison (2 for 11), but the only player who could be in their lineup that has had some success against the southpaw is Leury Garcia, who is 3 for 5.

The White Sox do have a lineup full of right-handed hitters, so that is perhaps an advantage there for the home team. Last season, 27 of the 33 homers Ray allowed came against right-handed hitters, and right-handed hitters hit 29 points higher against him than lefties did.

But for a dose of perspective, those averages were .216 and .187, and the homers per plate appearance were almost equal (one homer allowed every 23.5 plate appearances vs. left-handed hitters and one every 23.4 plate appearances vs. right-handed hitters).

Last year, Ray had two starts against the White Sox, registering a no-decision in each start, and he had a 1.35 ERA and 27 strikeouts and one walk in just 13.1 IP. In his start at U.S. Cellular Field, he struck out 13 (and walked none) and allowed one run and five hits in 6.1 IP.

So, even though this is a challenging matchup for him, he and the Mariners are good value in this spot, and so is the under.

Best Prop Bet for Mariners vs. White Sox: Robbie Ray OVER 6.5 Strikeouts (+104 at FanDuel Sportsbook)

Ray, the second favorite to be the MLB strikeout leader this season, had only five strikeouts in seven innings against the Twins, and the March/April stretch is historically his worst with regards to strikeouts per nine innings (10.7, with May the next lowest at 10.9).

But this number at plus odds? You don’t need to ask me twice.

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