Chargers vs 49ers, Odds & Picks: Preseason Finale Stays Under

Nate Hornung

Written by: Nate Hornung

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Chargers vs 49ers, Odds & Picks: Preseason Finale Stays Under cover


The San Francisco 49ers host the Los Angeles Chargers in the final game of the 2023 NFL Preseason.

Now this is a California battle I would love to see in the regular season, but alas we get it in the preseason tonight at Levi’s Stadium.

Let’s break down this preseason finale.

Chargers vs 49ers Game Information

Matchup Information

  • Venue & Location: Levi’s Stadium (Santa Clara, CA)
  • Date: Friday, August 25th, 2023
  • Kick Off: 10:00pm Eastern
  • Broadcast: NFL Network

Betting Odds


  • Chargers +7.5 (-110)
  • 49ers -7.5 (-110)


  • Chargers +290
  • 49ers -380


  • Over 37.5 (-115)
  • Under 37.5 (-105)

Chargers vs 49ers Best Bets

LAC/SF Under 37.5 (-105) Bovada

With the regular season in sight, I expect the starters to play a lot of downs in this game.

That means we see plenty of Justin Herbert, as well as plenty of Brock Purdy, whom the 49ers are going with as their starter.

They recently announced they would be shopping Trey Lance, and Sam Darnold will be Purdy’s backup.

Even with the starters playing plenty, I see them being cautious, as they should be.

It’s the last week of preseason, no one wants an injury right now.

Regardless, both of these defense are exceptional, and I think they can hold each other under 20 points. I see this being a boring, slow paced 14-10 victory for whomever holds the ball last.

With the 49ers moving forward with Purdy, they will heavily rely on their defense and skill players to carry them this season, but they will have their foot slightly off the gas in this preseason finale.

The test against Herbert and the Chargers is perfect to get the Niners defense locked in for another season.

Gimme this one staying under 38 points.

Chargers +7.5 (-110) BetOnline

With this being a game I see staying under, I also think the Chargers keep it within a touchdown.

Even being on the road, the Chargers won’t have to score very much to keep up.

This 49ers offense has only put up 28 total points this preseason, and they’ve given up over 50.

The Chargers blew out the Rams 34-17 in the Battle of LA, but then came up short against the Saints 22-17.

Scoring 51 and allowing just 39 in two games, I think the Chargers could cover this number and win outright while staying under.

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Nate Hornung
Nate Hornung

Nate has been a recreational sports bettor for about 5 years. In that time, he has grown to love the pursuit of winners and sticking it to The Man. Nate loves data and uses his understanding of numbers to help him be a more profitable sports gambler, however he will be the first to tell you this game is about more than just stats.

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