Yankees vs. Orioles Betting (July 22): Can O’s Pull Off Upset at Camden Yards?

Devon Platana

Written by: Devon Platana

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Yankees vs. Orioles Betting (July 22): Can O’s Pull Off Upset at Camden Yards? cover


Major League Baseball has another slate of exciting games scheduled for Friday, July 22. One matchup that fans are going to want to check out is a New York Yankees vs. Baltimore Orioles collision at Camden Yards this evening.

The Yankees emerge from the MLB All-Star break as the top team in the Majors. Having said that, things have been somewhat rocky lately. The Bronx Bombers are 3-7 in their last 10 games and dropped back-to-back contests in a doubleheader against the Houston Astros on Thursday.

Meanwhile, the Orioles have gone from basement-dwellers to the hottest team in the sport. Baltimore is 22-11 in its last 33 games and even though some of those wins haven’t come against the toughest opponents, more and more people are viewing the O’s as a threat.

The Yankees are sending right-handed pitcher Jameson Taillon in as their starter, while the Orioles will be represented by fellow righty Tyler Wells on the mound.

Here’s a look at BetOnline Sportsbook’s odds, along with the best bets to make, ahead of today’s Yankees vs. Orioles matchup.

New York Yankees vs. Baltimore Orioles Betting Odds and Matchup Information

Matchup Information

  • Matchup: New York Yankees (64-30, 27-18 road, 1st in the AL East) vs. Baltimore Orioles (46-46, 25-17, 5th in the AL East)
  • Venue & Location: Camden Yards (Baltimore, Maryland)
  • Date: Friday, July 22, 2022
  • Time: 7:05 p.m. Eastern Time
  • How to Watch Today’s Yankees vs. Orioles Game: MLB.TV, MLB Extra Innings, MASN

Yankees vs. Orioles Pitching Matchup

  • New York Yankees: Jameson Taillon (2022: 18 starts, 10-2, 3.86 ERA)
  • Baltimore Orioles: Tyler Wells (2022: 18 starts, 7-5, 3.38 ERA)

Yankees vs. Orioles Odds

Odds are via BetOnline. Odds from our other top reviewed and recommended online sportsbooks may also be included in this article.


  • New York Yankees -158
  • Baltimore Orioles +134


  • OVER 9 (-102)
  • UNDER 9 (-120)

Run Line

  • New York Yankees -1.5 (-102)
  • Baltimore Orioles +1.5 (-118)

Can Yankees Extend Dominance Over Orioles?

Even though the Yankees have seen better days, they have a solid opportunity to turn things around against the Orioles. Baltimore might be turning things around, however, New York has had its AL East rival’s number so far this season.

The two teams have already met 13 times this season, resulting in nine victories for the Yankees. In fact, New York has won eight of its last 10 meetings with Baltimore, outscoring the O’s by a combined score of 60-44 over that stretch.

It wouldn’t be a shock to find out that the Yankees love playing the Orioles this year. They’ve scored at least five runs against the O’s on eight different occasions this season. One person who’s, unsurprisingly, contributed to this offense is none other than Aaron Judge.

The MLB’s 2022 home run leader has 15 hits, six home runs and 11 RBIs in 12 games against the Orioles this season. He’s also recorded 35 total bases and has crossed home plate 13 times while batting .333.

It’ll be interesting to see how Taillon performs against the Orioles. The former 2010 first-round pick has faced Baltimore three times this season, going 1-0 with a 4.40 ERA and eight strikeouts over 14.1 total innings.

Someone that the Orioles will look to for some offense against the Yankees is Austin Hays. The 27-year-old outfielder is slashing .354/.415/.604 with two HRs and nine RBIs in 48 at-bats against New York this season. Rougned Odor isn’t too far behind him either with eight RBIs and a .308 batting average in 39 of his own ABs against the Yankees.

At the end of the day, the Yankees can’t afford to take the Orioles lightly. Sure, they’re at opposite ends of the division, but the fact is that Baltimore has been catching a lot of teams by surprise lately. Considering that the O’s have also won two of their last four games against the Yankees, an upset victory isn’t outside the realm of possibility.

Betting Trends for Yankees vs. Orioles

  • The Yankees are 2-5 straight up in their last seven games against AL opponents.
  • Baltimore is 8-0 straight up in its last eight home games.
  • The total has hit the over in six of the Yankees’ last seven games.
  • The total has hit the over in four of Baltimore’s last six games against the Yankees.

Yankees vs. Orioles Prediction and Best Bets

Yankees vs. Orioles Prediction: Orioles to win

Yankees vs. Orioles Best Bets: Orioles ML (+134 at BetOnline) & Over 9 (-102 at BetOnline)

Even though the Yankees are the clear favorites and have dominated the Orioles this season, I’m taking the O’s to pull off the upset win. I think that the Yankees’ recent stretch has left them vulnerable while the Orioles are surging for a reason.

Having said that, the best bet would be to take the Orioles at +134 on the moneyline. I’m also advocating for the over in this situation due to the two teams combining for at least nine runs in four of their last six games.

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Devon Platana
Devon Platana

Devon is a Master of Journalism graduate who joined the sports betting world in 2020. His favorite leagues to cover are the NHL, NBA and NFL, and has a soft spot for fantasy football specifically. Outside of sports, he enjoys the finer things in life like pasta, live music and getting even more tattoos.

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