Giants vs Phillies Picks & Prediction (Aug. 22): Castellanos Stays Hot at Home

Devon Platana

Written by: Devon Platana

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Giants vs Phillies Picks & Prediction (Aug. 22): Castellanos Stays Hot at Home cover


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The Philadelphia Phillies have a pep in their step after opening their three-game series against the San Francisco Giants with a win Monday. Game 2 of the Giants vs Phillies series takes place at 6:40 p.m. ET on Tuesday, leaving time to tell if Philadelphia can capitalize on its latest momentum.

The Phillies sent the Citizen Bank Park faithful home happy with a 10-4 win over the Giants last night. Four different Philly players record home runs — including Bryce Harper’s inside-the-park round-tripper — while Aaron Nola struck out five batters over seven innings for his 11th win of the campaign.

Can the Giants prove that last night’s loss was just a fluke? Or will the Phillies continue to solidify their wild-card positioning with another victory?

Betting News has all of your Giants vs Phillies betting needs covered, ranging from the latest odds to the best picks to make this evening.

San Francisco Giants vs. Philadelphia Phillies Betting Odds

SF vs. PHI Game Information

  • Matchup: San Francisco Giants (65-60, 30-32 Away) vs. Philadelphia Phillies (68-57, 35-24 Home)
  • Venue & Location: Citizens Bank Park (Philadelphia, Pennsylvania)
  • Date: Tuesday, August 22, 2023
  • Game Time: 6:40 p.m. Eastern Time
  • Where to Watch Giants vs Phillies: MLB.TV

Giants vs Phillies Odds

Game odds as of Tuesday, August 22 at 11:20 a.m. ET from Bovada. Odds from other sportsbooks may also be mentioned in this article.


  • San Francisco Giants +1.5 (-175)
  • Philadelphia Phillies -1.5 (+150)


  • Over 9 Runs (-120)
  • Under 9 Runs (+100)


  • San Francisco Giants +111
  • Philadelphia Phillies -133

Giants vs Phillies Probable Pitchers

  • Giants: Kyle Harrison (Making MLB debut)
  • Phillies: Taijuan Walker (24 starts — 13-5, 4.03 ERA)

Giants vs Phillies Betting Trends

  • San Francisco is 6-1 straight up in its last seven games against Philadelphia.
  • Philadelphia is 7-3 straight up in its last 10 home games.
  • The total has hit the under in four of San Francisco’s last six games.
  • The total has hit the over in each of Philadelphia’s last five games against the NL West.
  • The total has hit the over in five of the last six San Francisco-Philadelphia matchups at Citizens Bank Park.

Giants vs Phillies Game Preview

Last night’s win over the Giants was a long time coming for the Phillies. After all, Philadelphia had previously lost six straight games against San Francisco, having last beaten Gabe Kapler’s club on June 1, 2022.

Having said that, it wasn’t surprising to see the Giants come up short last night. They’ve been dreadful beyond belief on the road lately, now dropping 13 of their last 15 away matchups following yesterday’s loss.

Even worse is that the Giants only scored an average of 2.9 runs in their last 15 road outings while boasting a minus-2.5 average run margin during that stretch.

Meanwhile, the Phillies have been rock-solid in their own backyard. Philadelphia has played to a 7-3 record in their last 10 games at Citizen Bank Park, scoring at least six runs in each victory.

Nick Castellanos has been his team’s best player during that time, racking up four HRs with eight RBIs while slashing .326/.326/.628 in 43 at-bats.

giants vs phillies betting preview for aug. 22 game
Can Nick Castellanos step up again to help the Phillies continue their impressive home play?

The Giants chances of bouncing back from their latest loss hinge on how Kyle Harrison performs in his MLB debut. San Francisco’s No. 1 prospect has spent the entire 2023 campaign with Triple-A Sacramento, going 1-3 with a 4.52 ERA while averaging 14.5 strikeouts per nine innings across 21 starts.

Meanwhile, the Phillies are rolling with Taijuan Walker to pick up where Nola left off. Although he struggled early on in the year, Walker has been phenomenal since the beginning of June, playing to a 9-2 record with a 2.78 ERA in his last 12 appearances.

At the same time, the 31-year-old veteran arm hasn’t beaten the Giants in six years, going 0-2 with a 7.71 ERA in his last three outings against them.

Nevertheless, San Francisco’s recent road woes open the door for Walker to reverse that trend. He’s been great at home this season (6-2, 3.11 ERA in 12 starts) so as long as he sticks with what’s working, beating the Giants is an achievable goal.

Giants vs Phillies Prediction and Picks

Giants vs Phillies Prediction: Phillies 6, Giants 4

Giants vs Phillies Picks: Phillies ML (Best Value: -133 on Bovada ) & Nick Castellanos Over 1.5 Total Bases (+115 on Bovada)

After last night’s victory, I see the Phillies winning again tonight. The Giants have been dreadful on the road and it’s hard to say how Harrison will play in his debut. Meanwhile, Philly has been great at home and will ride Walker to another victory.

I also expect Nick Castellanos to continue his hot streak, hence why I’m taking him to record over 1.5 total bases (+115). He’s made good on this prop in seven of his last 11 home games, averaging 2.8 TBs during that run. Furthermore, he’s racked up 42 hits while slashing .313/.357/.530 against left-handed pitchers this season.

If Harrison shows any signs of shakiness in his first-ever start, you have to assume that a veteran like Castellanos will exploit any weakness he sees.

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Devon Platana
Devon Platana

Devon is a Master of Journalism graduate who joined the sports betting world in 2020. His favorite leagues to cover are the NHL, NBA and NFL, and has a soft spot for fantasy football specifically. Outside of sports, he enjoys the finer things in life like pasta, live music and getting even more tattoos.

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