Cardinals vs. Cubs (June 5): Back Wainwright and the Cards in Series Finale

After a doubleheader yesterday, the Cardinals and Cubs will wrap up a 5-game set this evening at Wrigley Field.

So far, the series is even at 2 wins apiece. This uncommon 5-game series will come to a close under the lights, with Adam Wainwright and a slew of other veterans for the Cardinals ready to take a series victory against their bitter rivals.

Albert Pujols played his 3000th game yesterday in Game 1 of the doubleheader. It was spoiled by great pitching for the Cubs, and the Cards had to settle for just the one win in Game 2.

The Cardinals and Cubs will not meet again in Chicago until late August, with another 5-game set scheduled. This game will decide who takes the bragging rights into their next series.

St. Louis Cardinals vs. Chicago Cubs Betting Odds and Matchup Information

Matchup Information

• Matchup: St. Louis Cardinals (31-23, 15-12 road, 2nd in the NL Central) vs. Chicago Cubs (23-31, 11-19 home, 4th in the NL Central)
• Venue & Location: Wrigley Field (Chicago, Illinois)
• Date: Sunday, June 5, 2022
• Time: 7:08 p.m. Eastern Time (6:08 p.m. local time)
• How to Watch Today's Cardinals vs. Cubs Game: ESPN

Cardinals vs. Cubs Pitching Matchup

• St. Louis Cardinals: Adam Wainwright (2022: 10 starts, 5-4, 2.75 ERA)
• Chicago Cubs: Justin Steele (2022: 10 starts, 1-5, 5.40 ERA)

Cardinals vs. Cubs Odds

Odds are via BetOnline. Odds from our other top reviewed and recommended online sportsbooks may also be included in this article.

Moneyline

• St. Louis Cardinals -132
• Chicago Cubs +112

Over/Under

• OVER 8.5 (-118)
• UNDER 8.5 (-104)

Run Line

• St. Louis Cardinals -1.5 (+128)
• Chicago Cubs +1.5 (-154)

Adam Wainwright Career vs. Chicago

Wainwright has appeared against the Cubs more than any other Major League Team. He has pitched in 53 games against Chicago, in which 44 of those were starts.

His 277.1 innings against the Cubs is second only to his totals against the Brewers. He has struck out 242 Chicago batters in his career and has walked 81.

Wainwright has an overall record of 17-13 against his division rival since the 2005 season. His ERA sits at 3.93 and his WHIP isn't bad at 1.28.

Wainwright is coming off his best start of the season against the San Diego Padres. He lasted 7 innings and struck out 10, while only allowing 2 hits. He did not pick up a decision in the game, but St. Louis did end up victorious.

He may be in his final season, as we have no knowledge of his plans after this season. He will take his career numbers into yet another matchup with the Cubs, a team that he knows inside and out.

St. Louis Cardinals vs. Chicago Cubs Prediction and Best Bets

Cardinals vs. Cubs Prediction: Cardinals to win

Cardinals vs. Cubs Best Bets: Cardinals moneyline (-132 at BetOnline)

The Cardinals send a veteran to the mound, while the Cubs will send a second year starter with an ERA over 5.00. The comparison sets up St. Louis for a good day at the plate, and in the pitching department.

Adam Wainwright has recorded 5 or more strikeouts in each of his last 3 starts against the Cubs. The contact will be light for Chicago, and the strikeouts will be plentiful.

St. Louis has also won their last 7 games against the Cubs following an extra innings win. After their 7-4 victory in 10 innings last night, they will be poised to strike again in the finale.