All-Star Game Picks & Predictions (7/15): Odds & Insights for Tonight’s Midsummer Classic

The MLB has reached its halfway point in the season and tonight, the stars come out to shine as bright as they can for the fans. The Midsummer Classic happens again as the American League takes on the National League in the 2025 MLB All-Star Game at Truist Park.

Get in on all the action with the best online sportsbooks and check out our expert MLB Picks below!

Check out our Expert MLB Picks!

MLB All-Star Game: American League vs. National League Picks & Predictions

Look, this is the All-Star Game. It's meant to be fun for the fans, and enjoyable for all. Let me be clear. This is not the game to drop a 10-unit whale on either side, the total, or any prop.

This matchup is for a few fun sprinkles here and there, and ultimately for all of us to watch some incredible baseball from all over the field. Pitchers and hitters alike will bring their best effort, as most will only see one inning on the mound, and just two at-bats at the plate if they are lucky.

With that being said, let's dive in and see what we are working with in tonight's All-Star Game!

Matchup Information – AL vs. NL – July 15

• Venue & Location: Truist Park (Atlanta, GA)
• Date: Tuesday, July 15, 2025
• First Pitch: 8:00 p.m. Eastern
• Broadcast: FOX

Starting Pitchers

• American League: Tarik Skubal (10-3, 2.23 ERA, 0.83 WHIP)
• National League: Paul Skenes (4-8, 2.01 ERA, 0.93 WHIP)

MLB All-Star Game Betting Odds

Odds are courtesy of BetOnline, an industry leader in the sports betting world. BetOnline offers a wide variety of markets paired with the most competitive lines available, making them the go-to site to place your bets. Sign up today with Promo Code FREE250 and get a 50% deposit match up to $250, as well as 100 Free Spins in the online casino.

Check out the Best USA Sportsbooks here!

Run Line

• American League +1.5 (-220)
• National League -1.5 (+186)

Moneyline

• American League +100
• National League -110

Total

• Over 7 (-121)
• Under 7 (+101)

Anyone want a history lesson?

The American League has won 10 of the last 11 All-Star Games, with their only loss since 2012 coming in 2023 in Seattle. Over the last 11 years, this total of seven is 5-4-2 to the under, pushing twice in 2019 and 2021. It went over last year by just one run, cashing for the first time since 2018.

We have Skubal and Skenes starting things off, but plenty of other great pitchers will be ready to come out of the bullpen. Historically, all pitchers will more than likely throw just one inning, with relievers sometimes throwing significantly less. As I stated above, take it easy on player props, especially overs. I would advise anyone to avoid them completely, but I know you sickos want some action tonight.

So, let's get into my favorite MLB All-Star Game picks.

MLB All-Star Game: American League vs. National League Best Bets

MLB All-Star Game Prediction: National League Wins, Over 7

Best Bet: National League F5 ML (-110) BetOnline

A solid line, push potential, and we get to go to bed early! We're hopefully getting in and out with a victory in the first five innings of the All-Star Game tonight.

I understand Tarik Skubal is on the mound, and I know how good he's been. But he's going to face Shohei Ohtani, Ronald Acuna Jr. and Ketel Marte, three extremely tough hitters, all batting at least .275 this season. Looking at the rest of the National League lineup, I simply like it more than their opponents.

The American League is starting players like Gleyber Torres and … *checks notes*… Javier Baez? Really? That guy's an All-Star starter? Just compare that to the National League.

Ohtani, Acuna, Marte, Freddie Freeman, Manny Machado, Kyle Tucker, Francisco Lindor, PCA… the starters in that dugout are much better on paper in my eyes, and that's enough for me to back them in this All-Star Game.

Please, please, please bet responsibly tonight. We've got a long second half of the season to wager on.

Still Didn't Get Your MLB Fix?

Here at Betting News, we offer Free Expert Picks for every major sports league. We also host daily streams on our Twitch Channel with our best bets, as well as sweat out games on Playback! Be sure to tune into everything we have going on at our Youtube, TikTok, and X pages as well.

For more MLB action, check out these pages below.

• AL & NL Cy Young Awards
• World Series Odds

Check Out All of Our Resources at Betting News