Eagles vs Cowboys Week 16 Betting: Can Dallas Take Advantage of Hurts-less Philly?

Devon Platana

Christmas Eve is packed with NFL Week 16 action, including an NFC East showdown between the Philadelphia Eagles and Dallas Cowboys. This is the second meeting of the season between the rivals and a victory here will play a key role in the division race. Needless to say, football enthusiasts won’t want to miss the next chapter of Eagles vs Cowboys history.

The Eagles continued to soar last week, picking up a 25-20 win over the Houston Texans to win their fifth game in a row. It wasn’t all good news, though, as quarterback Jalen Hurts suffered a sprained shoulder and is now questionable for Saturday’s contest.

Meanwhile, the only thing hurting about the Cowboys is their ego after their latest outing. After being up 27-10 over the Jacksonville Jaguars in the third quarter, the Cowboys began to unravel, ultimately losing 40-34 due to a pick-6 thrown by Dak Prescott in overtime.

Betting News has gathered the latest Eagles vs Cowboys odds from FanDuel Sportsbook to help shed some light on the situation, along with a prediction and best bets for the NFL Week 16 game.

Philadelphia Eagles vs Dallas Cowboys Week 16 Matchup Information and Betting Odds

Matchup Information

  • Matchup: Philadelphia Eagles (13-1, 7-0 Away) vs. Dallas Cowboys (10-4, 7-1 Home)
  • Venue & Location: AT&T Stadium (Arlington, Texas)
  • Date: Saturday, Dec. 24, 2022
  • Game Time: 4:25 p.m. Eastern Time
  • Eagles vs Cowboys Info: FOX

Eagles vs Cowboys Early Odds

Game odds are via FanDuel as of Tuesday, Dec. 20 at 8:47 a.m. ET. Odds from other top online sportsbooks may also be mentioned in this article.


  • Philadelphia Eagles +6 (-110)
  • Dallas Cowboys -6 (-110)


  • Over 46 Points (-110)
  • Under 46 Points (-110)


  • Philadelphia Eagles +220
  • Dallas Cowboys -270

Philadelphia Eagles vs Dallas Cowboys Betting Trends

  • Philadelphia is 7-0 straight up in its last seven road games.
  • Dallas is 7-0 straight up in its last seven home games.
  • Philadelphia is 3-7 against the spread (ATS) in its last 10 games against Dallas.
  • Dallas is 5-1 ATS in its last six home games against Philadelphia.
  • The total has hit the over in seven of Philadelphia’s last nine games.
  • The total has hit the over in five of Dallas’ last six games against the NFC East.

Philadelphia Eagles vs Dallas Cowboys Prediction and Picks

Eagles vs Cowboys Prediction: Cowboys 26, Eagles 23

Eagles vs Cowboys Picks: Eagles +6 (Best Value: -110 at FanDuel) & Over 46 Points (Best Value: -110 at FanDuel)

If Hurts is forced to miss Saturday’s contest, the Eagles could be in some trouble. He’s the straw that stirs the drink in Philly’s offense and has been having a career year, picking up 3,472 passing yards with 22 touchdowns to five interceptions. On top of that, he’s also turned 156 carries into 747 rushing yards and 13 TDs.

To further understand his importance to the team, you only need to look at FanDuel’s 2022 NFL MVP odds. Hurts currently sits second at +550 odds, trailing only the Kansas City Chiefs’ Patrick Mahomes (-350).

If Hurts is sidelined, Gardner Minshew will take his place under center. He was a reliable backup for the Eagles last season, making two starts (1-1) and recording 439 passing yards, four TDs and one pick. Still, he’d be tasked with going up against a Cowboys defense that has the second-most sacks (49) and ninth-most interceptions (12) in the NFL, so it’d be far from an easy night.

Unfortunately for Minshew, he hasn’t had the most luck against the Cowboys. Though he’s only faced them once, it ended up being a 51-26 loss for the Eagles in Week 18 of the 2021 campaign.

Needless to say, assuming Prescott plays up to his potential, the Cowboys will have the advantage under center. That requires him to play better than he has recently, though.

While Prescott has nine TDs while averaging 242.8 passing yards in his last four starts, he also has seven interceptions over that stretch. Considering how the Eagles pace the league with 15 picks this season, the veteran Dallas gunslinger can’t afford to make any mistakes.

With the Eagles able to clinch the NFC East with a victory, I see the Cowboys stepping up and grinding out the hard-fought win. It also helps that Dallas has won five of the last six Eagles vs Cowboys clashes at AT&T Stadium — including each of the last four. I know this is a different Philly team this time around, but Hurts’ injury will be the difference-maker here (whether he sits outright or plays at less than 100%).

Even though I expect the Cowboys to win, the Eagles’ defense will keep things closer than the spread implies. Dallas has just been sloppy lately and is 2-4 ATS in its last six games, so I have a hard time seeing Mike McCarthy’s team winning this by more than a touchdown.

I’m also willing to back the total going over 46 points. Four of the last five Eagles vs Cowboys games have hit the over, averaging 59 points in the last quartet of outings alone. With both offenses also flying over the last month or so, I see the over being reached.

Other Philadelphia Eagles vs Dallas Cowboys Resources

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Devon Platana
Devon Platana