Cowboys vs. Rams Week 5 Betting: Can Dallas Keep Things Close Against the Super Bowl Champs?

Devon Platana

Written by: Devon Platana

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Cowboys vs. Rams Week 5 Betting: Can Dallas Keep Things Close Against the Super Bowl Champs? cover


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Week 5 of the 2022 NFL season is just days away from beginning. As usual, the league has several interesting matchups to look forward to, including one involving two big-name teams as the Dallas Cowboys are set to collide with the Los Angeles Rams.

The Cowboys continue to rise without Dak Prescott under center. Cooper Rush has now led them to his third straight winning (starting his career 4-0), leading them to a lopsided 25-10 victory against the Washington Commanders.

Meanwhile, the Rams didn’t look like the same team that won the Super Bowl on Monday night. Los Angeles came up short against the rival San Francisco 49ers in Week 4, losing 24-9 in a forgettable game for the fanbase.

Betting News has gathered the latest Cowboys vs Rams odds from BetOnline Sportsbook to help shed some light on the situation, along with a prediction and best bets for the NFL Week 5 game.

Dallas Cowboys vs Los Angeles Rams Week 5 Matchup Information and Betting Odds

Matchup Information

  • Matchup: Dallas Cowboys (3-1, 1-0 Away) vs. Los Angeles Rams (2-2, 1-1 Home)
  • Venue & Location: SoFi Stadium (Inglewood, California)
  • Date: Sunday, Oct. 9, 2022
  • Game Time: 4:25 p.m. Eastern Time
  • Cowboys vs Rams Info: FOX, NFL+

Cowboys vs Rams Odds

Game odds are via BetOnline as of Tuesday, Oct. 4 at 8:38 a.m. ET. Odds from other top online sportsbooks may also be mentioned in this article.


  • Dallas Cowboys +4 (-106)
  • Los Angeles Rams -4 (-114)


  • Over 45.5 Points (-110)
  • Under 45.5 Points (-110)


  • Dallas Cowboys +176
  • Los Angeles Rams -210

Dallas Cowboys vs Los Angeles Rams Betting Trends

  • Dallas is 5-0 straight up in its last five games played in October.
  • The Rams are 5-0 straight up in their last five games against the NFC East.
  • Dallas is 13-3 against the spread (ATS) in its last 16 games against the NFC.
  • The Rams are 1-4 ATS in their last five home games.
  • The total has hit the over in five of Dallas’ last seven road games against the Rams.
  • The total has hit the under in 10 of the Rams’ last 13 games played in October.

Dallas Cowboys vs Los Angeles Rams Prediction and Picks

Cowboys vs Rams Prediction: Rams 21, Cowboys 19

Cowboys vs Rams Picks: Cowboys +4 (Best Value: -106 at BetOnline) & Under 45.5 Points (Best Value: -110 at BetOnline)

Man, the Rams sure have been a mess this season. While they had no issue beating underperforming teams like the Arizona Cardinals and Atlanta Falcons, they’ve lost by a combined score of 55-19 against the 49ers and Buffalo Bills — two potential Super Bowl contenders.

While the Cowboys haven’t exactly been beating the toughest teams in the league, momentum is on their side. Plus, the defense is playing like one of the NFL’s best units, giving up 308.5 total yards (No. 7) and 15.5 points (No. 3) per game.

Dallas is also tied for the ninth-most interceptions in the league with four. That doesn’t exactly bode well for a Los Angeles offense that’s seen QB Matthew Stafford throw an NFL-leading six interceptions.

What makes matters worse is that Stafford clearly isn’t healthy. He underwent an offseason procedure on his elbow that he’s still recovering from and the injury is supposed to persist throughout the campaign.

Needless to say, the Cowboys defense must put pressure on Stafford early and often. Fortunately, Dallas has an impressive pass rush led by the likes of Micah Parsons, DeMarcus Lawrence and Dorance Armstrong Jr. — a trio that’s already combined for 10 sacks, and 19 quarterback hits.

Will Rams QB Matthew Stafford bounce back against the Cowboys in Week 5?

Last year, the Rams had a top-10 defense. This year, they’re only in the middle of the pack across the board. Even though the Cowboys have a bottom-10 offense, they could be getting Prescott back in the lineup (assuming that the medical staff isn’t afraid of any setbacks for weeks after his thumb surgery).

A healthy Prescott would be bad news for the Rams, especially after he led the Cowboys to an NFL-leading 30.4 points per game in 2021. As great as Los Angeles’ offense looks on paper, the team has been held to 20 or fewer points in three of the four games this season.

I do think that the Rams are better than they’ve been playing and their first home game since Week 2 should get them back on track. Sometimes, being embarrassed in the Monday Night Football spotlight can bring out the best in a team and I expect the Super Bowl champions to rebound against a solid Cowboys squad.

Having said that, this won’t be a blowout. They might not be perfect, but the Cowboys are more than capable of keeping things close. Whether it’s Rush or Prescott under center, Dallas is good enough to give Los Angeles a challenge.

In addition to taking the Cowboys on the spread, I’m also backing the under. Neither offense has been clicking, proven by the two sides combining for 35.3 points per game thus far. With the projected total set at 45.5, the under is the way to go.

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Devon Platana
Devon Platana

Devon is a Master of Journalism graduate who joined the sports betting world in 2020. His favorite leagues to cover are the NHL, NBA and NFL, and has a soft spot for fantasy football specifically. Outside of sports, he enjoys the finer things in life like pasta, live music and getting even more tattoos.

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