MLB Picks and Props for Friday, May 29: Will Washington Work?

Written by: Danny Burke
Published: Fri May 29, 2026, 12:13 pm ET
Read Time: 4 minutes

mlb
Spread
Total
Moneyline
+1.5
-190
9
+100o
+104
Spread
Total
Moneyline
+1.5
-190
9.0
+100u
+120
There is no shortage of excitement on the diamond today, and I can't wait to dish out a few wagers from Friday's slate.
Below, I've got several MLB picks and props for Friday, May 29. Let's take a look.
MLB Picks and Props for Friday, May 29
San Diego Padres vs Washington Nationals
How about these Washington Nationals? They are coming off a 3-2 loss in Cleveland, but were in the midst of a four-game win streak entering that contest.
Conversely, the mood in the visitors' dugout is not the same, as the Padres have dropped four consecutive games. San Diego was swept at home by the Phillies, a series that included two shutout losses.
We'll see what their offense can do tonight when they face what appears to be a bullpen-oriented pitching plan. As of now, it seems Paxton Schultz will get the nod for the first inning before handing things over to Andrew Alvarez.
The 26-year-old left-hander has made four appearances this season, totaling 12.2 innings. He's posted a 2.84 ERA, 2.36 xFIP, 47% ground-ball rate and a 2.18 SIERA.
On the other side, Lucas Giolito will be making his third start of the season. His underlying metrics are picking up right where they left off, which is not a good thing. Last year with Boston, he finished with a 3.41 ERA, but also had a 5.01 expected ERA and 4.59 xFIP. Through two outings this season, he owns a 2.70 ERA, but a 6.31 xFIP.
I've been an avid fader of Lucas Giolito throughout the past several years, and I'll gladly take another opportunity to do so tonight.
Pick: Nationals Moneyline (-110)

Arizona Diamondbacks vs Seattle Mariners
- George Kirby Under 5.5 Strikeouts (-121)
- Zac Gallen Over 4.5 Strikeouts (-130)
MLB Picks & Props:
- Nationals Moneyline (-110 at Lucky Rebel)
- Zac Gallen Over 4.5 Strikeouts (-130 at Lucky Rebel)
- George Kirby Under 5.5 Strikeouts (-121 at Lucky Rebel)
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Danny Burke is a betting analyst with a decade of sports media experience. He got his start at the University of Nebraska-Lincoln, sharing picks on the local ESPN affiliate. After college, he hosted shows for VSiN in Las Vegas before returning to Chicago to launch 'Rush Hour', the first daily sports betting show from an Illinois casino. He also co-hosted 'Props and Locks' on Fox32’s Bears pregame show and ran 'Bet On, Chicago' on WLS-AM 890.
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