MLB Picks and Predictions for Tuesday, April 14: Are the Yankees Back?
Written by: Danny Burke
Published: Tue Apr 14, 2026, 12:20 pm ET
Read Time: 6 minutes
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Coming off a 2-0 performance last night, we'll look to keep things rolling into Tuesday's slate.
MLB Picks and Predictions for Tuesday, April 14
Washington Nationals vs Pittsburgh Pirates
The Pirates did a good job of raining on the Nationals' parade on Monday night, cruising to a dominant 16-5 win and snapping Washington's three-game win streak.
I'm hoping for a similar result when these teams meet again tonight.
Mitch Keller gets the nod for the home side, and he's been excellent to start his 2026 season. Keller's ERA sits at 1.00, and he's posting a .226 BABIP with an 88% left-on-base rate. His expected ERA comes in at 2.77 and his FIP sits at 2.80, though there is some concern with his 4.31 xFIP.
I don't want to completely disregard that, it's crucial to recognize, but I do believe he can stay above water enough to give his team the advantage.
Outside of Keller, a large reason I'm looking toward the Pirates is because of the pitcher they'll be facing.
Right-hander Miles Mikolas will be starting for Washington, and to no one's surprise, his struggles are persisting. Through three starts and 12.1 innings of work, his ERA sits at 12.41 with an 8.38 FIP, a 25% HR/FB rate and a .386 BABIP. Additionally, his WHIP is 2.35, and he's carrying a 47% hard-hit rate with a 14% barrel rate.
There's just nothing to like out of Mikolas' repertoire, and I'm banking on the Pirates being the next team to expose that.
Pick: Pirates Run Line -1.5 (+115)
San Francisco Giants vs Cincinnati Reds
Let's move on over to Cincinnati, where the Reds and Giants begin their three-game series at Great American Ballpark.
This may seem like a bold move, but I'm going to be fading Robbie Ray this evening. His 2.08 ERA through three starts looks great on the surface, but there are some reasons for concern. Ray's xFIP sits at 4.03, while his barrel rate is north of 11%.
The Reds have been solid against lefties thus far, ranking third in ISO (.171) and 13th in OPS (.669). I'm not necessarily expecting Ray to get blown up, but I do believe Cincinnati can inflict enough damage to warrant a wager on them.
What may seem even bolder is trusting their starting pitcher tonight in Brady Singer, who's posting a 7.71 ERA through three starts and 11.2 innings of work. Before overreacting, though, let's acknowledge that his xFIP sits at 2.92, he's got a ground-ball rate north of 42% and a Skill-Interactive ERA (SIERA) of 3.34.
Singer's numbers should look much better going forward, and it could start against a lackluster Giants lineup that ranks 28th in both OPS (.612) and wRC+ (73), while also sitting 27th in ISO (.110).
There's a reason why the Reds are trending toward being favorites in this game, and I'm going to side with that movement.
Pick: Reds Moneyline (-110)
Los Angeles Angels vs New York Yankees
The Yankees finally got back into the win column on Monday night, winning a high-scoring 11-10 battle against the Angels to snap their five-game losing streak.
Even though it was just one win, and a sloppy one at that, it's good to see one go through, and it should help boost momentum and confidence heading into the second game of this series.
What should also boost confidence for the Bronx Bombers is the arm they'll be facing in southpaw Reid Detmers.
I wouldn't be surprised if Detmers is in my top-three list of pitchers I've faded the most in my lifetime, and I'm going to do so again on Tuesday night.
Through three starts and 15.2 innings, Detmers has a 4.60 ERA and a 4.45 xFIP. His LOB% is weak at just 63%, as is his ground-ball rate, which sits at 34%.
Perhaps he survives against New York, given they're dead last in wRC+ and OPS against lefties so far this season, but there's still plenty of untapped power in that lineup that could easily come alive this evening.
Their offense should also get support from their starting pitcher, left-hander Ryan Weathers. He owns a 2.81 ERA, a 1.88 FIP and a 2.89 xFIP through three outings. He has yet to give up a home run and carries a 19% strikeout-to-walk ratio.
To the Angels' credit, they rank top-seven in both wRC+ and OPS against lefties, but they're lacking a bit of power, sitting 21st in ISO.
With the wind blowing out at Yankee Stadium, and considering Detmers is more of a home run liability than Weathers, this game should tilt in favor of the home club to produce plenty of runs and, ideally, win by more than one.
Pick: Yankees Run Line -1.5 (+115)
MLB Picks:
- Pirates Run Line -1.5 (+115 at Lucky Rebel)
- Reds Moneyline (-110 at Lucky Rebel)
- Yankees Run Line -1.5 (+115 at Lucky Rebel)
MLB Record: 25-18-1 (+6.17 units)
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Danny Burke is a betting analyst with a decade of sports media experience. He got his start at the University of Nebraska-Lincoln, sharing picks on the local ESPN affiliate. After college, he hosted shows for VSiN in Las Vegas before returning to Chicago to launch 'Rush Hour', the first daily sports betting show from an Illinois casino. He also co-hosted 'Props and Locks' on Fox32’s Bears pregame show and ran 'Bet On, Chicago' on WLS-AM 890.
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