MLB Picks and Predictions for Saturday, April 25

Danny Burke

Written by: Danny Burke

Published: Sat Apr 25, 2026, 1:33 pm ET

Read Time: 5 minutes

Aaron Judge and the Yankees are looking to extend their winning streak to six games tonight at home over Texas - Rangers Yankees Picks

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Happy Saturday, everybody! It's a beautiful day for some baseball, and I've got a few bets to dish out for today's card.

We're coming off a 1-2 effort on Friday night, thanks to the Dodgers blowing a late lead, but I'm feeling good about a bounce back, so let's dive into my favorite MLB picks and predictions for Saturday, April 25.

MLB Picks and Predictions for Saturday, April 25

Jeffrey Springs

Athletics vs Texas Rangers 

In the Lone Star State, Game 2 of this three-game set takes place between the Athletics and Rangers.

The A's captured Game 1, winning impressively, 8-1. Tonight, they look for another win with southpaw Jeffrey Springs leading the charge.

The left-hander has been solid through five starts, sporting a 3-1 record, a 3.34 ERA, and a 3.90 xFIP. There's much to like about his game at the moment, including a .211 BABIP, a 41% ground-ball rate, a sub-1.00 WHIP, and a low hard-hit rate of 31%.

It gets even better when you realize how poor the Rangers have been against lefties since the start of April, ranking dead last in wRC+, OPS, and ISO.

Meanwhile, the A's lineup will also be going against a left-hander, with MacKenzie Gore set to take the bump for the home team.

Gore has been fine, but there are some gaps. He has a 4.15 ERA, a 4.71 expected ERA, and a 4.44 FIP. His xFIP does show promise at 3.09, but his 24% HR/FB rate, 48% hard-hit rate, and 17% barrel rate suggest otherwise.

The Athletics haven't been much better against lefties this month, but if we narrow the sample to the past two weeks, there has been some improvement at the plate.

The visitors have a clear pitching edge and a slight offensive advantage, yet we're getting plus money on them. I'll gladly take a stab at the underdog in this spot.

Pick: Athletics Moneyline (+119)

Pittsburgh Pirates vs Milwaukee Brewers

Jacob Misiorowski is back at home tonight - Brewers Dodgers Picks

An underachieving Brewers team looks to turn the tide and snap its three-game losing streak at home against its division foe, the Pittsburgh Pirates, this evening.

They're in a quality position to do so, as their stud flamethrower, Jacob Misiorowski, is set to start for the Brew Crew.

He's lived up to the hype after a strong rookie season. Through five starts, he's posted a 3.04 ERA and a 2.79 xFIP, while logging a 27% strikeout-to-walk ratio.

The Pirates' offense has been fairly steady, sitting in the above-average range against right-handers, but Misiorowski is a different beast. It's hard to generate quality contact against him, and that's where Pittsburgh lacks, ranking 21st in ISO against RHP this month.

Milwaukee's offense hasn't been that impressive, though, but perhaps it can come alive against a familiar arm in Mitch Keller.

The Brewers have wreaked havoc against the 30-year-old, as he owns a 1-7 record with a 5.31 ERA in 12 appearances against them.

This feels like a strong spot for Milwaukee to get back in the win column.

Pick: Brewers Moneyline (-136)

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New York Yankees vs Houston Astros 

How about those scorching-hot Yankees? New York extended its win streak to seven after pummeling the Astros on Friday night, 12-4.

I'm expecting the momentum to carry over into Saturday night, as they face a vulnerable arm in Mike Burrows.

Through five starts and 26.2 innings of work, the 26-year-old right-hander has a 6.75 ERA and a 4.82 FIP. Additionally, his BABIP is extremely high at .378, along with a 1.69 WHIP and a 14% HR/FB rate.

Over the past two weeks, the Yankees rank first in ISO (.226), fourth in OPS (.810), and fifth in wRC+ (124) against righties.

This is a scary spot for Burrows.

On the flip side, the Astros will face a lefty in Ryan Weathers, who has an impressive 3.18 ERA and a 2.74 xFIP. He's been a bit susceptible to the long ball himself, but he should be able to manage difficult situations better than Burrows.

Houston ranks 22nd in ISO (.124), 21st in OPS (.677) and 19th in wRC+ (91) over the past couple of weeks.

If the Astros had a better pitcher on the bump, I might've stayed away, but given Burrows' unreliability and the Yankees' hot bats, it's hard to ignore the Bronx Bombers.

Pick: Yankees Moneyline (-146)

MLB Picks: 

MLB Record: 33-24-1 (+8.19 units)

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Danny Burke
Danny Burke

Danny Burke is a betting analyst with a decade of sports media experience. He got his start at the University of Nebraska-Lincoln, sharing picks on the local ESPN affiliate. After college, he hosted shows for VSiN in Las Vegas before returning to Chicago to launch 'Rush Hour', the first daily sports betting show from an Illinois casino. He also co-hosted 'Props and Locks' on Fox32’s Bears pregame show and ran 'Bet On, Chicago' on WLS-AM 890.

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