Steelers vs Colts Week 12 MNF Betting: Expect Low Offensive Numbers at Lucas Oil Stadium

Devon Platana

We’re nearing the final stretch of the 2022 NFL season now that Week 12 is finally here. The Pittsburgh Steelers and Indianapolis Colts need victories to salvage their respective seasons and they’ll get a chance to do so in front of the Monday Night Football lights. In other words, this Steelers vs Colts clash is one that you won’t want to miss.

After being victorious in Week 10, the Steelers followed up their win with a 37-30 loss to the rival Cincinnati Bengals over the weekend. Pittsburgh only led for 3:57 in the entire game, proving that Mike Tomlin’s team has a long way to go before being treated like a legitimate threat.

Meanwhile, the Colts were on their way to victory in Week 11 before blowing a fourth-quarter lead to the Philadelphia Eagles, eventually losing 17-16. Time is running out for Indianapolis to make a playoff push, leaving time to tell if the team can rediscover its groove against the slumping Steelers.

Betting News has gathered the latest Steelers vs Colts odds from FanDuel Sportsbook to help shed some light on the situation, along with a prediction and best bets for the NFL Week 12 game.

Pittsburgh Steelers vs Indianapolis Colts Week 12 Matchup Information and Betting Odds

Matchup Information

  • Matchup: Pittsburgh Steelers (3-7, 1-4 Away) vs. Indianapolis Colts (4-6-1, 2-3 Home)
  • Venue & Location: Lucas Oil Stadium (Indianapolis, Indiana)
  • Date: Monday, Nov. 28 2022
  • Game Time: 8:15 p.m. Eastern Time
  • Steelers vs Colts Info: ESPN, Wish TV

Steelers vs Colts Early Odds

Game odds are via FanDuel as of Tuesday, Nov. 22 at 8:42 a.m. ET. Odds from other top online sportsbooks may also be mentioned in this article.


  • Pittsburgh Steelers +2.5 (-105)
  • Indianapolis Colts -2.5 (-115)


  • Over 39.5 Points (-110)
  • Under 39.5 Points (-110)


  • Pittsburgh Steelers +122
  • Indianapolis Colts -144

Pittsburgh Steelers vs Indianapolis Colts Betting Trends

  • Pittsburgh is 2-7 straight up in its last nine games.
  • Indianapolis is 1-9 straight up in its last 10 games against the AFC North.
  • Pittsburgh is 5-1 against the spread (ATS) in its last six games against Indianapolis.
  • Indianapolis is 1-6 ATS in its last seven games as the favorite.
  • The total has hit the under in six of Pittsburgh’s last seven road games against Indianapolis.
  • The total has hit the under in 14 of Indianapolis’ last 16 games.

Pittsburgh Steelers vs Indianapolis Colts Prediction and Picks

Steelers vs Colts Prediction: Colts 20, Steelers 17

Steelers vs Colts Picks: Steelers -2.5 (Best Value: -115 at FanDuel) & Under 39.5 Points (Best Value: -110 at FanDuel)

While the Steelers and Colts have had plenty of exciting battles in the past, this isn’t the Ben Roethlisberger versus Peyton Manning era anymore. Instead, fans will be treated to a battle between struggling offenses as rookie QB Kenny Pickett leads Pittsburgh against an ageing Matt Ryan in Indianapolis.

There’s no doubt that this MNF clash features two of the worst offenses that the NFL has to offer. Though both teams have their fair share of playmakers, the Steelers are only averaging 17.0 points per game (No. 28) while the Colts are operating on a 15.7 PPG clip — second-worst in the league.

On top of that, Pittsburgh’s road offense (13.2 PPG) is the second-worst of all 32 teams. Although it isn’t much, Indianapolis might have the small advantage here by averaging 20.6 points through five games at Lucas Oil Stadium.

If the Colts want to be victorious, Ryan must take advantage of the Steelers’ poor secondary. Though the former NFL MVP has only put up 435 passing yards with one touchdown pass in his last two outings, he still completed an impressive 73.3% of his 60 passing attempts.

Matt Ryan must take advantage of the Steelers’ poor pass defense to lead the Colts to victory.

Now, Ryan and co. go up against a Pittsburgh defense that surrenders an NFL-worst 272.1 passing yards per game. In other words, the 37-year-old gunslinger needs to get the likes of Michael Pittman, Alec Pierce, Parris Campbell and Jonathan Taylor involved early and often.

It’s also hard to trust a Steelers offense that’s been held to an average of just 8.7 points in their last three road games. It doesn’t help that Pickett has only thrown for two TDs with four interceptions over his last four games, getting sacked 16 times in that span.

With the Colts allowing fewer than 180 passing yards in five of their last eight games, I don’t see the Steelers getting much going here. Even if the ‘Black and Yellow’ turns to the run game, Indianapolis gives up the 11th-fewest rushing yards this season.

Although Steelers head coach Mike Tomlin also has the experience advantage behind the bench, the Colts are playing solid football with the newly hired Jeff Saturday at the helm. After nearly beating the Eagles last week, I’m looking to the Colts to be victorious this time around.

The Steelers’ seven losses have come by an average margin of 12.9 points, so I have no issues backing the Colts as 2.5-point spread favorites. It’s not a huge sample size, but they are 3-2 against the spread at home this season.

With the two sides also averaging 32.7 combined points this season, I’m also inclined to back the under on the total. In addition to the total going under in six of the last seven Steelers vs Colts tilts at Lucas Oil Stadium, Pittsburgh has failed to surpass 39.5 points in three of its last five games while Indianapolis has failed in eight of 11 games this season.

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Devon Platana
Devon Platana