The Panthers won for the third time in their last four games with a 37-23 victory over the Detroit Lions last week. Carolina’s rushing attack was the star of the show as the backfield combined for 320 rushing yards and a trio of touchdowns on 43 carries.

Meanwhile, the Buccaneers went back and forth with the Arizona Cardinals in Week 16, eventually walking out with the 19-16 overtime victory. Despite dealing with a foot injury, running back Leonard Fournette played a huge role in the win, rushing for 72 yards on 20 carries while also hauling in nine receptions for another 90 yards.

Betting News has gathered the latest Panthers vs Buccaneers odds from FanDuel Sportsbook to help shed some light on the situation, along with a prediction and best bets for the NFL Week 17 game.

Carolina Panthers vs Tampa Bay Buccaneers Week 17 Matchup Information and Betting Odds

Matchup Information

• Matchup: Carolina Panthers (6-9, 1-5 Away) vs. Tampa Bay Buccaneers (7-8, 4-4 Home)
• Venue & Location: Raymond James Stadium (Tampa, Florida)
• Date: Sunday, Jan. 1, 2023
• Game Time: 1 p.m. Eastern Time
• Panthers vs Buccaneers Info: FOX

Panthers vs Buccaneers Early Odds

Game odds are via FanDuel as of Tuesday, Dec. 27 at 8:29 a.m. ET. Odds from other top online sportsbooks may also be mentioned in this article.

Spread

• Carolina Panthers +3 (-110)
• Tampa Bay Buccaneers -3 (-110)

Over/Under

• Over 39.5 Points (-110)
• Under 39.5 Points (-110)

Moneyline

• Carolina Panthers +136
• Tampa Bay Buccaneers -162

Carolina Panthers vs Tampa Bay Buccaneers Betting Trends

• Carolina is 1-9 straight up in its last 10 road games.
• Tampa Bay is 4-1 straight up in its last five games against Carolina.
• Carolina is 1-4 against the spread (ATS) in its last five games against Tampa Bay.
  Tampa Bay is 1-9-1 ATS in its last 12 games played on Sunday.
• The total has hit the over in seven of Carolina’s last 10 games played in January.
• The total has hit the over in four of Tampa Bay’s last six games against Carolina.

Carolina Panthers vs Tampa Bay Buccaneers Prediction and Picks

Panthers vs Buccaneers Prediction: Buccaneers 21, Panthers 17

Panthers vs Buccaneers Picks: Buccaneers -3 (Best Value: -110 at FanDuel) & Under 39.5 Points (Best Value: -110 at FanDuel)

This is the second meeting of the season between these NFC South rivals and it’s safe to say that the first one didn’t go the Buccaneers’ way.

The Panthers were victorious in the first meeting back in Week 7, picking up the 21-3 win as the Bucs’ offense was completely iced out. It was also the first time that Carolina beat Tampa Bay since Tom Brady joined the former in 2020.

Prior to that, Brady & co. had four straight wins against the Panthers, averaging a whopping 37.5 points in victory. Unfortunately, the Buccaneers haven’t been putting up anywhere close to those numbers this season, averaging just 17.7 points per game (No. 28).

Even if the offense hasn’t been there, I still do like the Buccaneers’ chances of winning this weekend. It’s just hard to imagine Brady losing to the Panthers twice in one season, especially if this does end up being his final campaign. He’s going to want to go on one more deep playoff run, which would require winning the NFC South.

After all, a victory here would lock up the division for Tampa Bay.

The Panthers have also been terrible on the road this season, going just 1-5 away from home. Their road offense (19.0 PPG) ranks 10th-worst in the NFL and their minus-7.5 scoring margin in away games is the league’s fourth-worst mark.

The Buccaneers have been far from perfect at home, but they have won four of their last six games against the Panthers at Raymond James Stadium. On top of that, Tampa Bay hasn’t even lost at home to Carolina since October 2019, further highlighting the former’s advantage when playing down south.

And even though the Buccaneers lost to the Panthers earlier this year, Brady still had 290 passing yards in defeat. After Carolina just allowed the Lions to rack up 336 passing yards last week, there should be enough opportunities for Brady to do some damage as well — especially if he can connect with his pass-catchers in the end zone.

With the Buccaneers being a plus-8.9 in their last eight games with the Panthers, I see the former covering the 3-point spread this weekend. This is one of those games that should be close until the end, but Brady has the experience edge that has me believing that he can pull away when it matters the most.

Considering how neither offense has been lights out this year, I’m expecting a low-scoring battle. They already combined for only 24 points earlier this campaign and considering how the total has gone under in 11 of Tampa Bay’s 15 games thus far, I’m expecting more of the same on New Year’s Day.

Other Carolina Panthers vs Tampa Bay Buccaneers Resources

• Panthers vs Buccaneers Consensus Picks, Score Projections & Betting Stats

Other NFL Week 17 Articles on Betting News

• Cowboys vs Titans Thursday Night Football Prediction & Prop of the Game: Will Thursday Night Football be a blowout or can the slumping Titans keep it close in Music City?