49ers vs Jaguars, Prediction & Best Bets: Jacksonville Stuns San Francisco

Nate Hornung

Written by: Nate Hornung

Last Update: Sun Nov 12, 2023, 7:49 am ET

Read Time: 4 minutes

Updated 2027 NFL Super Bowl odds for all 32 teams. We break down the early favorites and the best value futures to bet now.

nfl

San Francisco 49ers logo
FINAL
Jacksonville Jaguars logo

San Francisco 49ers

34

Jacksonville Jaguars

3
See Picks & Statistics For The Game

We've got quite the battle on Sunday in Florida as the San Francisco 49ers travel to face the Jacksonville Jaguars.

We've got our best bets an prediction as both of these potential playoff teams look to keep their seasons trending in the right direction.

After opening up the season to a 4-0 start, the 49ers have now lost three straight games, two of them being on the road. Now they face a very dangerous Jaguars team.

Jacksonville started off 1-2 through three weeks of play, and fans maybe wondered if they would make the playoffs like last year. Nevertheless, the Jags turned it around.

They've won five straight games since then, including wins over the Bills and Colts. Now after two weeks on the road, the Jaguars will look to impress their home fans once again on Sunday.

Let's break this game down and find our best bets!

5/5 Review Rating
Bonus & Benefits
100% Up to $1,000
See our review »
Free Contests for Real Money
Bet on Esports
Sportsbook, Casino & Racebook

49ers vs Jaguars Game Information

Matchup Information

  • Venue & Location: EverBank Stadium (Jacksonville, FL)
  • Date: Sunday, November, 12th, 2023
  • Kick Off: 1:00pm Eastern
  • Broadcast: FOX

Betting Odds

Odds Courtesy of Bovada.

Spread

  • 49ers -3 (-110)
  • Jaguars +3 (-110)

Moneyline

  • 49ers -170
  • Jaguars +145

Total

  • Over 45 (-115)
  • Under 45 (-105)

Free NFL Picks: 49ers vs Jaguars

Best Bets 49ers Jaguars

This is a huge game for the 49ers young QB. People were talking about Brock Purdy as a legit MVP candidate, and then they lost three games straight and that talk has disappeared.

Losing Deebo Samuel definitely hurts this team, and they also missed McCaffery for a good chunk of one of those losses. However, the 49ers are still an elite team and need to find ways to win.

After scoring 30+ in their first 5 games, the 49ers have only put up 17 points in each of their three losses. Even with their elite defense, this has not been enough to get the job done.

And the Jaguars will be tough to stop.

Trevor Lawrence has led this team to score over 27 PPG in their five straight wins. Based on the recent trends with the 49ers, they might be able to win with less than that.

The Jaguars TT is sitting at 20.5 with the over juiced to -125.

And I'm hoping on board.

The Pick: Jaguars TT over 20.5 (-125) BetOnline

Best Bets 49ers Jaguars

In my eyes the Jaguars have solidified themselves as a playoff team once again, especially considering the rest of their division. Plus, they could make some noise if they continue to play this way.

Three touchdowns, that's all we need from this Jags team, and that might be asking a lot considering they are one of the worst RedZone teams in the NFL.

Jacksonville currently ranks 26th in the NFL in RedZone scoring percentage only including touchdowns. They only find the end zone on 47% of trips to the RedZone.

I'm betting on them to figure it out at home, even against this tough defense.

4.8/5 Review Rating
Bonus & Benefits
55% Welcome Bonus w/ code BNBOL55
See our review »
Up to $250 in Free Bets + 100 Spins
$10 Cash Bonus w/ Code BNEWS
Fastest Payouts

NFL Player Props Bets

Travis Etienne over 22.5 Receiving Yards (-113) Bovada

Best Bets 49ers Jaguars

I'll keep this one quick, because the numbers do the talking.

He's cleared this line in 6/8 games this season, and exploded for 48+ receiving yards on three separate occasions. He had 70 yards last week, including a 56 yard TD reception.

Etienne averages 4.4 targets and 3.4 catches per game this year, for an average of 33.3 receiving yards per game.

The last two games, he's seen 11 total targets, and he's cleared in 4 straight games.

Now, here's what San Francisco's Defense has allowed running backs to do out of the air.

  • Joe Mixon: 3 receptions, 23 yards
  • Cam Akers: 2 receptions, 30 yards
  • Kareem Hunt: 3 receptions, 24 yards

It won't take much, and it could arguably be done in just one screen play.

This line is too low, and I'm all over it.

Interested in More Content?

Get FREE Picks and Props Weekly

Sign up for
THE WEEKENDER NEWSLETTER

Follow me on X @Shaggy_Bets for all of my picks and sports opinions!

Be sure to check out all things Betting News on X and Twitch!

Tune in to one of our several weekly streams! You won't regret it!

And go get some MERCH at our Betting News Store!

In need of a sportsbook? Check out one of our favorites below and sign-up for a bonus!

1
4.9/5 Review Rating
Bonus & Benefits
Up to $1,250 + 50 Free Slots Spins
See our review »
$1,250 Welcome Bonus
Bet Live on Your Favorite Sports
Earn More with Rebel Rewards!
2
4.8/5 Review Rating
Bonus & Benefits
55% Welcome Bonus w/ code BNBOL55
See our review »
Up to $250 in Free Bets + 100 Spins
$10 Cash Bonus w/ Code BNEWS
Fastest Payouts
3
4.7/5 Review Rating
Bonus & Benefits
Get 20% Cashback Weekly
See our review »
10% Daily Cashback
10% Weekly Cashback Every Thursday
Get VIP Rewards for Your Sports Bets
4
4.6/5 Review Rating
Bonus & Benefits
100% up to $1,000 Sign-Up Bonus
See our review »
Bonus Code: WELCOME1000
Monthly Cash Prizes
Vast Lines and Games Selection
5
4.5/5 Review Rating
Bonus & Benefits
55% Welcome Bonus w/ code BNSB55
See our review »
$250 in Free Bets with First Deposit
Same Game Parlays
Frequent Odds Boosters
6
4.4/5 Review Rating
Bonus & Benefits
50% Up to $750
See our review »
Best Prop Bets Selection
Boosted Odds on Parlays
One of the Oldest and Trusted Sites
7
4.3/5 Review Rating
Bonus & Benefits
Multiple Bonuses for New Players
See our review »
125% Promo Bucks Up to $2,500
100% Cash Bonus Up to $2,000
Weekly Rebates!
8
4.2/5 Review Rating
Bonus & Benefits
Deposit $100, Get $50 Free
See our review »
Reduced Juice for Spreads & Totals
Fast Crypto Deposits & Payouts
Winners & High Rollers Welcome!
9
4.1/5 Review Rating
Bonus & Benefits
125% Welcome Bonus
See our review »
Anonymous Crypto Betting
125% Welcome Bonus
Great Live Betting Selection
10
4.0/5 Review Rating
Bonus & Benefits
125% Deposit Bonus
See our review »
Fast & Easy Payouts
Best Deposit & Free Play Bonuses
Largest Selection of Sports & Games

Still Here?

Check out everything we have to offer at Betting News!

We really are All About the Game!

See our Matchup - Free Picks & Stats
Nate Hornung
Nate Hornung

Nate has been a recreational sports bettor for about 5 years. In that time, he has grown to love the pursuit of winners and sticking it to The Man. Nate loves data and uses his understanding of numbers to help him be a more profitable sports gambler, however he will be the first to tell you this game is about more than just stats.

This site contains commercial content. We may be compensated for the links provided on this page. The content on this page is for informational purposes only. Betting News makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.