#21 Missouri vs #15 Alabama: NCAA Football Predictions, Odds & Best Bets

Nate Hornung

Written by: Nate Hornung

Last Update: Thu Oct 24, 2024, 3:23 pm ET

Read Time: 6 minutes

Jalen Milroe takes on the Missouri Tigers at home

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Missouri Tigers logo
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Alabama Crimson Tide logo

Missouri Tigers

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Alabama Crimson Tide

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See Picks & Statistics For The Game

Another HUGE SEC Showdown is happening in Bryant-Denny Stadium this Saturday, as the Alabama Crimson Tide host what's left of the Missouri Tigers. What I mean by that is the Tigers are suffering from tons of injuries. As of Thursday morning, it looks like leading rusher Nate Noel won't even make the trip to Alabama, while QB Brady Cook is doubtful with an ankle injury. This means that Drew Pyne will be leading the offense into enemy territory.

Pyne has completed just 67% of his passes this year, and was 10/21 for 78 yards against Auburn when he filled in. Straight up, he is nowhere near as talented as Brady Cook, and I could see this one getting very ugly for the Tigers. Not only are you missing your Senior QB, but also your leading rusher as well, meaning Marcus Carroll should be ready to go against a tough Alabama defense.

As for the Crimson Tide, this is not a week you want to face them. They now have 2 losses in the SEC, and hopes of making not only the conference championship, but the CFP as a whole are dwindling fast. They are going into a bye week before going to Baton Rouge, so I have full faith that Alabama comes ready to play this weekend. It's a big bounce back spot against a team who is dealing with plenty of injuries, so let's dive in and see if we can back the Tide.

Missouri Tigers vs Alabama Crimson Tide: Tigers Limp into Tuscaloosa

Alabama looks to bounce back with a win on Saturday

Can Alabama take down Missouri at home?

Matchup Information – Missouri vs Alabama

  • Venue & Location: Bryant-Denny Stadium (Tuscaloosa, AL)
  • Date: Saturday, October 26th, 2024
  • Kick Off: 3:30pm Eastern
  • Broadcast: ABC

Betting Odds

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Spread

  • Missouri +17 (-123)
  • Alabama -17 (+103)

Money Line

  • Missouri +520
  • Alabama -700

Total

  • Over 50.5 (-117)
  • Under 50.5 (-103)

Can Tigers Compete Without Cook?

Can the Tigers win without Cook and Noel?

Brady Cook is doubtful to play this weekend in Tuscaloosa

Look, Nate Noel has run for 500 of the team's 1,200 rushing yards this season, with Brady Cook adding another 100. The Tigers will need to make up a ton of offensive production this Saturday, and I don't think they have it in them. We might see three different QBs for Missouri, as I don't think Pyne has it in him, and Eli Drinkwitz may be forced to give someone else a chance.

Ultimately, I am kicking myself for not taking Alabama at -13 on Wednesday before this news dropped. It was staring into my soul, I knew it was the right side, but failed to press the button before the news dropped. I still endorse Bama at -17, although I would recommend getting 16.5 if you can find it. But as for me, I will be holding off out of principle since I missed the best number by a landslide. Don't be afraid, Alabama rolls in this game.

The Tigers struggle to stop the run, especially against dual threat QBs… do you know where this is going?

While I do lean with Alabama, and also with the under, I won't be taking either. I trust the Crimson Tide defense to slow down a depleted Missouri offense, but I am worried about their offense running it up. Alabama could easily score 40 in this game and ruin our over by themselves. Instead, what I'll do is back the Alabama QB to come back to life.

Missouri Tigers vs Alabama Crimson Tide Best Bets

Can Milroe run all over Missouri at home?

We faded Milroe last weekend, but this Saturday we cheer him on

Missouri vs Alabama Prediction: Alabama Wins & Covers, No Thoughts on Total

Best Bets: Jalen Milroe Over 41.5 Rushing Yards (-114) BetOnline

Last week, we faded Milroe with success against Tennessee, cashing his under 46.5 rushing yards. This weekend, we take the other side, and back him to get it done with his legs.

Milroe has 91 carries for this Alabama team, with their lead RB, Jam Miller, only having 63 throughout the year. The QB should have plenty of opportunities, as he runs 13 times per game. He's only cleared this line in 3/7 games this season, ending with 36 against South Carolina, but in this matchup, he should avoid sacks.

Milroe has been sacked 9 times in the last 3 games, but Missouri is terrible against the run and only gets to the quarterback a couple times per game. And like I said, they do not contain dual threat QBs.

Against Missouri, Vandy QB Diego Pavia lead the Commodores with 17 carries for 84 yards and was only sacked once. Connor Weigman, a non-mobile QB for A&M, somehow ran 5 times for 33 yards and was only sacked once. Milroe should have no problem avoiding pressure, rolling out of the pocket and making some plays with his legs. He's had a 25+ yard rush in 4/7 games and a 10+ yard rush in every single contest. Give me Milroe to eat on Saturday.

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Nate Hornung
Nate Hornung

Nate has been a recreational sports bettor for about 5 years. In that time, he has grown to love the pursuit of winners and sticking it to The Man. Nate loves data and uses his understanding of numbers to help him be a more profitable sports gambler, however he will be the first to tell you this game is about more than just stats.

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