#10 Missouri vs. #7 Miami (FL) Picks and Predictions: Round of 64
Written by: Nate Hornung
Published: Thu Mar 19, 2026, 5:10 pm ET
Read Time: 5 minutes
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The Missouri Tigers are basically playing a home game on Friday as they take on the Miami Hurricanes in St. Louis in the Round of 64. I have to give Miami props for finishing third in a much weaker ACC than we expected, but are they prepared for the Big Dance? Outside of conference play, the Hurricanes played the 30th easiest schedule in all of college hoops, but Missouri's schedule outside the SEC was a bit easier. Now the two might be in for a wake up call as they go head to head on Friday night.
Check out our March Madness Betting Guide to get in on all the action this month!
Best Bet: Missouri ML (+106) Lucky Rebel Sportsbook
Go check out what else I've got on my daily card, and view the latest odds at the best online sportsbooks.
#10 Missouri Tigers vs. #7 Miami (FL) Hurricanes NCAA Basketball Insights
Malik Reneau leads the Hurricanes in scoring, putting up 18.8 points per game on 54.9% from the field
As I mentioned, neither team played a tough non conference schedule. But both were still in the top 80 overall in strength of schedule, with the Tigers breaking the top 50. All year long, Missouri has been skating by with wins, but I can't let you forget, they beat the No. 1 seeded Florida Gators this season in Columbia. However, they ended the season on a three game losing streak, but neither the Tigers or Hurricanes won a game in their conference tournament.
And one will lose on Friday and watch their season come to an end. Neither team is extremely fast or slow, and both score around 80ish points per contest. Will the Hurricanes be able to pull this off as short favorites in what might feel like a road environment?
Matchup Information – Missouri vs. Miami – March 20
- Venue & Location: Enterprise Center (St. Louis, MO)
- Date: Friday, March 20, 2026
- Kick Off: 10:10 p.m. Eastern
- Broadcast: truTV
Missouri vs. Miami Betting Odds
Odds are courtesy of Lucky Rebel, one of our favorite online sportsbooks, as of March 19, 2026 at 3:07 p.m. eastern. Sign up today with and get a $1,250 deposit bonus, as well as 50 slot spins immediately. Lucky Rebel Sportsbook offers a wide variety of unique markets across nearly every sport imaginable.
Spread
- Missouri +2 (-114)
- Miami (FL) -2 (-106)
Moneyline
- Missouri +106
- Miami (FL) -128
Total
- Over 147 (-110)
- Under 147 (-110)
#10 Missouri vs. #7 Miami (FL) NCAA Basketball Picks and Predictions
Missouri is just 1-7 since 2011 in the NCAA Tournament. Will they find a win on Friday?
Missouri vs. Miami Prediction: Missouri Wins Outright, Over 147
Best Bet: Missouri ML (+106) Lucky Rebel Sportsbook
I was able to snag the best number possible on Sunday, getting the Tigers for (+130). But anything with a plus sign is a good play in my eyes. And I'll be the first to admit, I am not a Mizzou guy. I hate them. I bleed red and blue (Rock Chalk). And I don't have very many advanced analytics to back this up, which is how I usually like to look at things. This is more of a gut play.
Miami does not play well on the perimeter. They don't take very many threes and can't make their free throws. I'll give them their flowers, they are one of the best rebounding teams in the nation on both sides of the ball, but Mizzou is a team that crashes the offense glass as good as anyone. They have the bodies down low to hang with the size of the Hurricanes and combat their inside scoring.
Add in the fact that this is just a short two hour drive for anyone in Columbia (plenty of Mizzou faithful in St. Louis), and I don't see Miami pulling this off. Take the points if you want, but I have the Tigers knocking off the Hurricanes on Friday.
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Check Out the Other March Madness Content from Betting News
For college basketball bettors, March Madness is the most wonderful time of the year. And at Betting News, we have you covered for this festively fun season with expert picks throughout the tournament from Nate Hornung and Eddie Griffin, consensus picks for every March Madness game from the First Four to the Final Four, a rundown of the best March Madness betting sites, and more.
Also, through our streams and social media channels, you can get even more insight from Nate and other members of the Betting News team, as well as offer your own thoughts and tips for the tournament.
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Nate has been a recreational sports bettor for about 5 years. In that time, he has grown to love the pursuit of winners and sticking it to The Man. Nate loves data and uses his understanding of numbers to help him be a more profitable sports gambler, however he will be the first to tell you this game is about more than just stats.
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