DePaul vs. Xavier: The Musketeers Revenge | January 31, 2026

Colby Marchio

Written by: Colby Marchio

Last Update: Sat Jan 31, 2026, 7:04 am ET

Read Time: 4 minutes

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DePaul heads to Cincinnati for a rematch with Xavier, and the spot sets up well for the Musketeers. The Blue Demons won the first meeting 86 to 77, but have struggled mightily away from Chicago. DePaul is still searching for its first road conference win and has seen sharp drops in efficiency on both ends when traveling. Xavier, meanwhile, has played its best basketball at home and has shown strong response spots after losses this season. With revenge on the table and DePaul's road issues well documented, Xavier looks primed to take advantage on Saturday.

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DePaul vs. Xavier Odds 

Can the Blue Demons secure their first conference win away from home?

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Spread

DePaul: +3.5 (-110)

Xaveir: -3.5 (-110)

Total

Over: 150.5 (-110)

Under: 150.5 (-110)

Moneyline

DePaul: +152

Xavier: -183

DePaul vs. Xavier Bet

Another day, another DePaul report from your favorite unbiased two-time DePaul alum. The Blue Demons head to Cincinnati to take on the Musketeers for the second time this month. The last time these two met, DePaul came out on top 86 to 77. In that matchup, the Blue Demons were a 2.5-point favorite. Will the Musketeers be out for revenge after losing three straight? I expect them to come out starving for a win.

Xavier has only faced one conference opponent twice early in conference play, that team is Creighton. The first meeting saw the Bluejays dominate 98 to 57 in Cincinnati. They recently met again in Omaha, where Xavier lost by just one. If the Musketeers can show that level of motivation in a road revenge spot, I expect even more focus at home against DePaul on Saturday.

Road Woes

The Blue Demons have not secured a road win since their first true road game on December 13, when they defeated Wichita State 61 to 58. They are 0-5 on the road in conference play, and their entire team performance drops once they leave Chicago.

Haslametrics grades DePaul as the 33rd worst team in away home court metrics. Overall, DePaul has shined defensively this season, ranking in the top five across most defensive categories. However, on the road their eFG% drops to second worst in the Big East, they rank dead last in 3 point percentage defense, and sit ninth in free throw rate defense.

Offensively, DePaul has struggled all season, and those issues are magnified on the road. They rank bottom three in adjusted offensive efficiency, turnover rate, offensive rebounding, free throw rate, and block percentage. Their scoring dips from around 76 points per game to 66.5 away from home.

Xavier has played some of its best basketball at home this season. Through five home conference games, the Musketeers rank third in offensive turnover rate, first in defensive rebounding, third in free throw rate defense, and third in defensive block percentage.

Overall, across 13 home games, Xavier ranks 12th in protecting the basketball, 76th in defensive rebounding, and 67th in defensive block percentage. They take a healthy volume of three point shots and convert them at a solid rate. DePaul has limited three-point attempts well, but when opponents get those looks, they are hitting nearly 42%.

This feels like another spot where the Blue Demons come up short. They peaked with the Marquette win a few weeks ago and have since lost at Butler, beaten Seton Hall at home, and dropped a game at Georgetown on Wednesday in the Hoyas own revenge spot. I think Xavier gets theirs on Saturday.

Best Bet: Xavier -3.5 (-110) on Lucky Rebel

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Colby Marchio
Colby Marchio

Former D1 (club) baseball player, Colby has been betting since his college days at DePaul, where he had to endure the worst collegiate basketball the Big East has ever seen. He is an advanced analytics nerd and has never seen an underdog he has not liked. Hot. Corn. Bull. It does not matter the dog he loves them all.

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