Creighton vs. DePaul: Odds & Best Bets | February 11, 2026

Colby Marchio

Written by: Colby Marchio

Published: Wed Feb 11, 2026, 10:24 am ET

Read Time: 4 minutes

Will Creighton take down the Mountaineers and move on to the CBC Championship on Sunday? Creighton West Virginia Picks

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Creighton Bluejays logo
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DePaul Blue Demons logo

Creighton Bluejays

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DePaul Blue Demons

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See Picks & Statistics For The Game
A gritty Big East battle takes center stage in Chicago as Creighton visits DePaul in a matchup defined by defense. The Bluejays arrive with momentum after a strong win over Seton Hall, while the Blue Demons look to snap a four game slide and steady themselves in conference play. Both teams lean on their defensive identity, limiting clean looks and protecting the paint. Offense has been inconsistent on both sides, especially from the perimeter. With tempo expected to stay controlled and half court possessions likely to dominate, this shapes up as a physical, lower scoring contest where every trip matters.

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Last 7 Days: 17-5-1 (+10.66 Units)

Last 30 Days: 41-28 (+9.78 Units)

Creighton vs. DePaul Odds 

Can the Blue Demons protect their home court this evening and come out on top?

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Spread

Creighton: +1.0 (-110)

DePaul: -1.0 (-110)

Total

Over: 142.0 (-108)

Under: 142.0 (-112)

Moneyline

Creighton: -106

DePaul: -115

Creighton vs. DePaul Bet

Welcome back to another DePaul report from your completely unbiased two time alumnus of the most beautiful university in Chicago. Tonight, the Creighton Bluejays head into the South Loop coming off an impressive win over Seton Hall. On the other side, the Blue Demons are struggling, having lost four straight and, shockingly, not covering at the rate they were entering conference play. That stretch included a 6-1 ATS start in conference. Regression was always likely, but are the Blue Demons in position to grab a win against a subpar Creighton team? Let us get into it.

Defensive Identities

When in doubt, take the under. This feels like a spot where both defenses show up. Why? Because that is the identity of both teams. DePaul has built its entire season around defense. Head coach Chris Holtmann made that clear from the first practice. The defense has kept them competitive in many games. The offense, however, has kept them from finishing the job.

Creighton is still searching for its identity after losing key pieces from the past few seasons. On the road, the Bluejays rank 34th in adjusted defensive efficiency. They excel at keeping opponents off the line, attacking the glass, and defending the perimeter. Offensively, they have been underwhelming. Creighton ranks 32nd in two-point percentage and does a solid job attacking the rim. However, they do not get to the line often, do not convert free throws at a high rate, and their perimeter shooting ranks in the bottom 45 nationally.

At home, DePaul has hovered around a top 50 defense for most of the season. They do a strong job clogging the lane, which will matter against a Creighton team that offers little from beyond the arc. Even if the Bluejays try to generate outside looks, DePaul ranks 39th in three-point rate defense. Offensively, the Blue Demons have struggled at home, ranking 248th in effective field goal percentage, 283rd in two-point percentage, and near the bottom nationally in offensive block percentage.

The pace should not be blazing, though it may be slightly quicker than some metrics suggest. Haslametrics ranks DePaul 279th in tempo overall, but at home they rise to 160th on Bart Torvik. Creighton sits 222nd in overall pace and moves up to 181st on the road. Even with a modest bump in tempo, it does not concern me. Both teams hang their hats on defense. This sets up as a lower scoring game filled with tough shots and plenty of empty possessions.

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Colby Marchio
Colby Marchio

Former D1 (club) baseball player, Colby has been betting since his college days at DePaul, where he had to endure the worst collegiate basketball the Big East has ever seen. He is an advanced analytics nerd and has never seen an underdog he has not liked. Hot. Corn. Bull. It does not matter the dog he loves them all.

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