Major League Soccer Picks and Predictions: Saturday’s MLS

Nate Hornung

Written by: Nate Hornung

Published: Sat Apr 11, 2026, 11:25 am ET

Read Time: 5 minutes

Luis Suarez has one goal in just three appearances for Inter Miami this MLS season - MLS Picks

MLS

A full slate of Major League Soccer is upon us this Saturday, as we have 13 matches on today's slate. There are a few this afternoon but most of the board doesn't go off until 7:00 p.m. eastern, giving us plenty of time to break down our best bets. Let's look at our soccer analyst's favorite MLS picks for this massive betting board!

We are off to a hot start on the pitch, and we are coming off an MLS sweep last weekend. Let's see if we can do it again!

  • MLS YTD
  • 8-5 (61.5%)
  • +3.44u

Head over to our MLS Picks Page for our expert's soccer analysis, or read my best bets below.

Major League Soccer: Saturday's Predictions April 11

Inter Miami vs. New York Red Bulls MLS Picks

Lionel Messi and Inter Miami earned a draw in their first match at Nu Stadium, but they are looking for their first win in their new home tonight - MLS Picks

Lionel Messi and Inter Miami earned a draw in their first match at Nu Stadium, but they are looking for their first win in their new home tonight

Best Bet: Inter Miami -1.5 (+103) Lucky Rebel Sportsbook

Back Inter Miami at home today with me to win by multiple goals. This will be there second official match at Nu Stadium after it opened last week. They played Austin FC to a 2-2 draw in the debut, so they are still looking for their first win in their new home. They face a Red Bulls team that started off hot but has since cooled down with their new manager, Michael Bradley, leading the team. New York has allowed 13 goals in just six MLS matches so far this season, and Miami is more than capable of netting at least two.

They've netted 11 in their six matches so far, including four in a come from behind win against Orlando City. This team has scored six times in their last three matches overall, and you cannot deny their talent. They are stacked. Lionel Messi has the skill to take over a game and score multiple goals whenever he wants, and New York has not performed well on the road this year.

They lost to Charlotte 6-1 in their last away game, and played Toronto to a 1-1 draw, needing a stoppage time goal to earn a point. Against a very motivated Miami team, this one could get ugly.

Prediction: Inter Miami Wins 3-1 (+900)

Sporting KC vs. San Jose Earthquakes MLS Picks

Niko Tsakiris has solidified himself as an integral part of this Earthquakes' starting lineup - MLS Picks

Niko Tsakiris has solidified himself as an integral part of this Earthquakes' starting lineup

Best Bet: San Jose Earthquakes ML (-145) Lucky Rebel Sportsbook

Do your line shopping, because I was able to snag this at (-135), but I am willing to pay this juice on San Jose. For starters, they already beat this Sporting KC team 3-0 to start the season out in California. Tonight in Kansas City, I don't see anything changing. Sporting absolutely sucks. They've lost two in a row, to Real Salt Lake on the road and to the Colorado Rapids at home, two teams they should've beaten. Not only did they lose, but they were destroyed on the scoreboard, losing 4-1 and 3-1 in those contests. I do not see them fixing their problems at home tonight.

San Jose has been off to a tremendous start, netting 10 total goals while only conceding one as they post a 5-0-1 record early on this season. The offense is clicking (like always), and the defense has severely stepped up their game and made it tough on other teams to score. Sporting KC simply does not have the firepower to take down the Earthquakes, and again, I am more than willing to pay this juice to watch it happen.

Prediction: San Jose Earthquakes Win 3-0 (+1500)

Still Want More Soccer Content?

Here at Betting News, we offer Free Expert Picks for every major sports league. We also host daily streams on our Twitch Channel with our best bets, as well as sweat out games on Playback! Be sure to tune into everything we have going on at our Youtube, TikTok, and X pages as well. Be sure to follow my personal X account as well, @Shaggy_Bets for my full daily card.

Get FREE Picks and Props Weekly

Sign up for
THE WEEKENDER NEWSLETTER

Nate Hornung
Nate Hornung

Nate has been a recreational sports bettor for about 5 years. In that time, he has grown to love the pursuit of winners and sticking it to The Man. Nate loves data and uses his understanding of numbers to help him be a more profitable sports gambler, however he will be the first to tell you this game is about more than just stats.

This site contains commercial content. We may be compensated for the links provided on this page. The content on this page is for informational purposes only. Betting News makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.