CBS Sports

Dratings

DunkelIndex

OddsShark

Sports Betting Dime

Moneyline

Total

Point Spread

Away/Home

Wins

Ov / Un

Avalanche

Ryan Hofer

Jack O'Brien

Andrei Buyalsky

Shane Bowers

Nils Aman

Nazem Kadri

Tyson Jost

Matthew Stienburg

Jayson Megna

Alex Newhook

Stefan Matteau

Colby Ambrosio

Jean-Luc Foudy

Matej Kaslik

Nathan MacKinnon

Callahan Burke

Gabriel Fontaine

Artem Anisimov

Nico Sturm

Andrew Cogliano

Ben Meyers

Jacob MacDonald

Devon Toews

Ryan Murray

Roland McKeown

Mitchell Smith

Cale Makar

Graham Sward

Nicolas Savoie

Sergei Boikov

Jordan Gross

Drew Helleson

Bowen Byram

Keaton Middleton

Danila Zhuravlyov

Erik Johnson

Rhett Rhinehart

Dennis Gilbert

Samuel Girard

Justin Barron

Nate Clurman

Sean Behrens

Nick Leivermann

Jack Johnson

Andreas Englund

Josh Manson

Trent Miner

Jonas Johansson

Hunter Miska

Shamil Shmakov

Justus Annunen

Pavel Francouz

Darcy Kuemper

Jett Alexander

Kiefer Sherwood

Kurtis MacDermid

Andre Burakovsky

J.T. Compher

Artturi Lehkonen

Darren Helm

Gabriel Landeskog

Tyler Weiss

Mikhail Maltsev

Andreas Wingerli

Sampo Ranta

Taylor Makar

Dalton Smith

Nikolai Kovalenko

Logan O'Connor

Mikko Rantanen

Oskar Olausson

Nicolas Aube-Kubel

Martin Kaut

Valeri Nichushkin

Alex Beaucage

Nick Henry

Dylan Sikura

Tarun Fizer

Blues

Logan Brown

Sam Anas

Robert Thomas

Oskar Sundqvist

Zachary Bolduc

Tyler Bozak

Brayden Schenn

Tanner Kaspick

Nolan Stevens

Dakota Joshua

Jordan Kyrou

Dylan Peterson

Nathan Todd

Ivan Barbashev

Ryan O'Reilly

Matthew Peca

Klim Kostin

Nikita Alexandrov

Keean Washkurak

Justin Faulk

Steven Santini

Colton Parayko

Calle Rosen

Tyler Tucker

Andrei Pervyshin

Torey Krug

Jake Walman

Noah Beck

Scott Perunovich

Marco Scandella

Niko Mikkola

Tommy Cross

Matthew Kessel

Tyson Galloway

Robert Bortuzzo

Leo Loof

Josh Wesley

Griffin Luce

Nick Leddy

Jordan Binnington

Colten Ellis

Joel Hofer

Will Cranley

Konstantin Barulin

Charlie Lindgren

Vadim Zherenko

Ville Husso

Kyle Konin

Jon Gillies

Jake Neighbours

Mackenzie MacEachern

Pavel Buchnevich

Hugh McGing

Brandon Saad

David Perron

Nathan Walker

Kyle Clifford

Dimitri Semin

James Neal

Evgeny Skachkov

Vladimir Tarasenko

Mathias Laferriere

Simon Robertsson

Alexei Toropchenko

Victor Alexandrov

Ivan Vorobyov

Michael Frolik

Away/Home Defense

Away/Home Offense

Defense

Offense

Colorado Avalanche vs St. Louis Blues Picks

Enterprise Center

<p>The Colorado Avalanche and St. Louis Blues meet at Enterprise Center for Game 6 of their second round series. The Avalanche hold a 3-2 series edge, but could not get the job done in Game 5, letting the Blues score late and steal the game in overtime.</p>
<p>The Avalanche held a 3-0 lead in Game 5 before St. Louis stormed all the way back to tie it with 3 unanswered goals. Colorado took the lead back with less than 3 minutes on the clock, but could not close out. </p>
<p>The Blues scored with under a minute left to send Game 5 to overtime. In the extra session,  Tyler Bozak was the hero for St. Louis. He found the back of the net on St. Louis’ second shot of the frame to send us back to Enterprise Center for a Game 6.</p>
<p>The rare defensive collapse by Colorado in Game 5 allowed the Blues to climb back into the series, but that’s not to say that St. Louis has the ability to come all the way back from a 3-1 deficit.</p>
<p>The Blues have hope, but with Colorado still undefeated on the road, Game 6 is trending in the way of the favorites. According to <a href="https://www.williamhill.us/us//us/in/bet/icehockey?id=b7b715a9-c7e8-4c47-af0a-77385b525e09">Bovada Sportsbook</a>, the Avalanche have the best chance to advance to the Western Conference Final on Friday night to face the Edmonton Oilers, who are awaiting the winner of this series.</p>
<h2 id="a3tn8">Colorado Avalanche vs. St. Louis Blues Betting Odds and Matchup Information</h2>
<h3 id="49ra8">Matchup Information</h3>
<ul>
<li>Colorado Avalanche (3-2) vs St. Louis Blues (2-3)</li>
<li>Venue: Enterprise Center (St. Louis, MO)</li>
<li>Date: Friday, May 27, 2022</li>
<li>Time: 8:00 p.m. ET</li>
<li>How to Watch Avalanche vs Blues Game 6: TNT</li>
</ul>
<h2 id="7bto">Avalanche vs. Blues Game 6 Odds</h2>
<p><em><strong>Avalanche vs. Blues odds are via our top reviewed and <a href="/best-online-sportsbooks/">recommended sportsbooks</a>.</strong></em></p>
<h3 id="bgu0v"><strong>BetOnline</strong></h3>
<ul>
<li><strong>Puck Line: </strong>Avalanche -1.5 (+134), Blues +1.5 (-162)</li>
<li><strong>Over/Under: </strong>Over 6.5 (-128), Under 6.5 (+104)</li>
<li><strong>Moneyline: </strong>Avalanche -176, Blues +146</li>
</ul>
<h3 id="eri2h">Bovada Sportsbook</h3>
<ul>
<li><strong>Puck Line: </strong>Avalanche -1.5 (+145), Blues +1.5 (-170)</li>
<li><strong>Over/Under: </strong>Over 6.5 (-115), Under 6.5 (-105)</li>
<li><strong>Moneyline: </strong>Avalanche -170, Blues +145</li>
</ul>
<h3 id="39j3o">BetUS</h3>
<ul>
<li><strong>Puck Line: </strong>Avalanche -1.5 (+135), Blues +1.5 (-159)</li>
<li><strong>Over/Under: </strong>Over 6.5 (-113), Under 6.5 (-108)</li>
<li><strong>Moneyline: </strong>Avalanche -167, Blues +145</li>
</ul>
<h2 id="etm1e">Players to Watch</h2>
<p>For the Avalanche, Nathan MacKinnon is on a hot streak. He recorded a hat trick their last time out to bring his goal total for the postseason to 8. He has recorded at least one point in all but one game against the Blues this season.</p>
<p>For the Blues, watch out for David Perron. He has 9 goals this postseason, and he has scored 4 times against the Avalanche during the series. He added two more goals against the Avs in the regular season, and if he scores once, he’s usually going to find the back of the net at least once more.</p>
<p>Both goaltenders will have to be sharper in Game 6. In the series, there have been a combined 35 goals scored between the two teams. St. Louis is still going with backup Ville Husso due to the injury to Jordan Binnington. Colorado sends Darcy Kuemper back out after a rough Game 5.</p>
<p>This will be a fun, close game to the very end. Both teams have proven themselves with the weapons they have. Even though St. Louis is at home, Colorado has not lost on the road during the Stanley Cup Playoffs. </p>
<h2 id="1bogi">Avalanche vs Blues Prediction and Best Bets</h2>
<p><strong>Avalanche vs. Blues Prediction: </strong>Avalanche 5 Blues 3</p>
<p><strong>Avalanche vs. Blues Best Bets: </strong>Avalanche -1.5 (+145 at <a href="https://www.williamhill.us/us//us/in/bet/icehockey?id=b7b715a9-c7e8-4c47-af0a-77385b525e09">Bovada Sportsbook</a>) and Over 6.5 total goals (-113 at <a href="https://pa.betrivers.com/?page=sportsbook&amp;l=RiversPittsburgh&amp;group=1000093657&amp;type=prematch#home">BetUS</a>)</p>
<p>The Avalanche should fix their mistakes from Game 5 and lock down a win in Game 6. Expect them to pull away late and continue their impressive road winning streak.</p>
<p>The last three games between the two teams have gone Over the total goal line. With this trend intact, and both teams scoring back-and-forth, I am confident there will be more than 6.5 goals scored in this matchup.</p>
<p><script>if(window.strchfSettings === undefined) window.strchfSettings = {};window.strchfSettings.stats = {url: "https://betting-news.storychief.io/en/avalanche-vs-blues-2022-game6-odds-prediction?id=950402056&type=2",title: "Avalanche vs. Blues Game 6 Odds and Prediction: Avs to Win Game and Series",id: "4af471aa-0a59-40f0-a023-eeb51e59464b"};(function(d, s, id) {var js, sjs = d.getElementsByTagName(s)[0];if (d.getElementById(id)) {window.strchf.update(); return;}js = d.createElement(s); js.id = id;js.src = "https://d37oebn0w9ir6a.cloudfront.net/scripts/v0/strchf.js";js.async = true;sjs.parentNode.insertBefore(js, sjs);}(document, 'script', 'storychief-jssdk'))</script></p>

Avalanche vs. Blues Game 6 Odds and Prediction: Avs to Win Game and Series

Nicholas Plowfield

More NHL News

NHL Best Bet 12/4/2025

NHL Best Bet 12/2/2025

NHL: Capitals vs. Islanders Picks and Odds | November 30, 2025

NHL Best Bet 11/26/2025

NHL: Bruins vs. Islanders Picks and Odds | November 26, 2025