Indiana vs. USC: Odds & Best Bets | February 3, 2026

Colby Marchio

Written by: Colby Marchio

Last Update: Tue Feb 03, 2026, 10:02 am ET

Read Time: 4 minutes

Can USC find a way to upset Wisconsin at the Kohl Center? USC Wisconsin Picks

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Indiana Hoosiers logo
FINAL
USC Trojans logo

Indiana Hoosiers

75

USC Trojans

81
See Picks & Statistics For The Game
Late night Big Ten action heads to Southern California as Indiana wraps up its west coast trip against USC. The Hoosiers are playing some of their best basketball, coming off impressive wins over Rutgers, Purdue, and UCLA, but travel and tempo loom large in this spot. USC has been inconsistent, yet the Trojans excel at getting to the free throw line and defending the perimeter, two areas that can trouble Indiana away from home. With USC ranking 21st in pace at home and Indiana struggling in road games against top 100 teams, this matchup sets up as a key contrast in styles late tonight.

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Indiana vs. USC Odds 

How will Conor Enright and the Hoosiers perform tonight in Southern California?

You can find all of these great College Basketball odds on Lucky Rebel. Get a $1,250 deposit bonus & 50 Slot Spins when you sign up!

Spread

Indiana: +1.0 (-112)

USC: -1.0 (-108)

Total

Over: 152.0 (-110)

Under: 152.0 (-110)

Moneyline

Indiana: -107

USC: -114

Indiana vs. USC Bet

Late night Big Ten action heads to Southern California, as the Indiana Hoosiers wrap up the second and final game of their road trip out west. Meanwhile, the USC Trojans look to clean things up, as they are 2-3 over their last five games. Those two wins came by a combined five points. Can the Trojans secure a commanding win tonight against an Indiana team playing some of its best basketball? Let us get into it.

A team I have been waiting to turn things around after a sluggish January is the Indiana Hoosiers. This group came out of the gates back in November, terrorizing everyone in its path. Once they got a taste of playing away from home, the struggles followed. Fast forward to the last three games, where Indiana demolished the Scarlet Knights on the road by 23, then took down Purdue at home 72 to 67, and followed that up by beating UCLA on the road 98 to 92 in double overtime. This team is flying too close to the sun and has endured a ton of travel over the last 11 days. I want to be all over the Trojans at home tonight.

USC is coming off a three point win over Rutgers this past Saturday. Were Eric Musselman's boys looking ahead to hosting the Hoosiers, as they failed to cover the 12.5-point spread against Rutgers? Possibly.

Against top 100 teams, the Trojans sit at 7-6 straight up, with their most notable wins coming against Wisconsin, Seton Hall, and Minnesota. In those 13 games, this squad owns a top 75 offense and defense. USC has excelled at getting to the line, which is important because fouling is something the Hoosiers struggle with on the road. On top of that, the Trojans are one of the best teams in the country at defending the perimeter, which will be crucial tonight. Indiana ranks eighth in three-point rate this season and shoots at an efficient clip.

Road games against top 100 teams have been an issue for the Hoosiers, who are 1-4 straight up. They rank 21st worst in offensive rebounding, 19th worst in offensive block percentage, and 37th worst in free throw rate defense. Their three-point percentage drops from 35.7% on the season to 29.3%, while still attempting the deep ball at the third highest rate in the country.

This game should have some pep due to how fast the Trojans like to play. At home this season, they rank 21st in pace of play. Meanwhile, the Hoosiers away from home sit at 245th. USC needs to take Indiana out of its comfort zone and force a faster tempo. If the Trojans can dictate pace and make Indiana play their style, they should come out on top in this one.

Best Bet: USC Moneyline (-114) on Lucky Rebel

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Colby Marchio
Colby Marchio

Former D1 (club) baseball player, Colby has been betting since his college days at DePaul, where he had to endure the worst collegiate basketball the Big East has ever seen. He is an advanced analytics nerd and has never seen an underdog he has not liked. Hot. Corn. Bull. It does not matter the dog he loves them all.

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