Phillies vs. Astros: Pitcher Prop Predictions | June 25, 2025
Written by: Colby Marchio
Last Update: Wed Jun 25, 2025, 3:30 pm ET
Read Time: 4 minutes
mlb
Phillies vs. Astros: Zack Wheeler has been nearly untouchable in June, and tonight he draws a road start against the surging Astros. Despite Houston's recent hot streak, they have not faced an arm like Wheeler's in weeks. We are targeting his strikeouts prop and laddering it with confidence.
For additional information on picks, props, moneylines, and more on today's slate, take a look at our MLB Picks Page or our MLB Odds Page, here.
Write Up Transparency
Be sure to follow me on X/Twitter @ColbyMBets to get my full card every day! Picks are always FREE.
Last Month: 71-157 (-16.44u)
Last Week: 15-38 (-6.17u)
Phillies vs. Astros Best Bet – June 25
Will we see another quality start out of Zack Wheeler tonight in Houston?
Check out BetOnline's New No Strings Welcome Offer that gives new MLB players up to $250 in Free Bets and 100 Free Casino Spins with their first deposit. Find out more about this Promotion as well as lots of other Free Sportsbook Promos right here!
Coming off a dominant performance against the Mets last Friday—five shutout innings, four hits allowed—Zack Wheeler looks to stay hot in Houston. The Astros have been playing well in June, but this is a different test. Wheeler has been locked in, and tonight, we are targeting his strikeouts prop.
Through three starts this month, the Phillies ace owns a 1.06 ERA, has allowed just three runs on 11 hits, struck out 24, and walked four over 17.0 innings pitched. He is in another gear right now, and we are taking the over on his strikeouts prop set at 6.5 (-140).
Zack Wheeler Trends
Wheeler holds the fourth-best pitcher rating of the day, according to Batters-Box. When given an elite rating, he delivers. In 23 such starts over the past three seasons, he has gone over 6.5 strikeouts 73% of the time, recorded 8+ in 47%, and 9+ in 30%. When he has an elite strikeout matchup, those numbers rise to 78%, 63%, and 41%, respectively. On the road, in elite strikeout spots, he clears those same marks 81%, 63%, and 27% of the time (in 11 starts). It is not a massive sample, but for pitchers, double digits is noteworthy.
This season, Wheeler averages 7.4 strikeouts per game on the road with a 2.86 ERA and a .201 opponent batting average.
The Astros are playing solid baseball, but they have feasted on bad teams this month—Pirates, Guardians, White Sox, Twins, Athletics, and Angels. In June, they are slashing .259/.322/.418 with a .740 OPS. However, their plate discipline remains average. Over the past seven days, they rank 10th-worst in strikeout rate; over the past 14, they are 12th-worst—hovering between 22% and 24%.
The best arm they have faced in June is Paul Skenes. He went eight innings, allowed one run on three hits, and struck out eight. The rest of their opponents have been mediocre at best. Skenes is the real deal—and so is Wheeler, one of the most consistent arms in the league.
That is why I have Wheeler's strikeouts laddered up to 11 tonight.
Best Bet: Zack Wheeler Over 6.5 Strikeouts (-140) odds via BetOnline
Interested in More Content?
Get FREE Picks and Props Weekly
Sign up for
THE WEEKENDER NEWSLETTER
Follow me on X @ColbyMBets for all my picks and sports opinions. Follow Betting News on 'X' and Twitch and catch us on stream! Betting News is also on TikTok! Follow us for more picks and news every day!
In need of a sportsbook? Check out one of our favorites below among our best online sportsbooks and sign-up for a bonus!
Check Out All of Our Betting Resources at Betting News
- Picks & Odds for the NFL
- NFL Betting Guide for Beginners
- Pick & Odds for NCAAF
- NCAAF Betting Guide for Beginners
- Picks & Odds in the MLB
- MLB Betting Guide for Beginners
- Picks & Odds in the NBA
- NBA Betting Guide for Beginners
- Picks & Odds in the NHL
- NHL Betting Guide for Beginners
More Betting Stories
Former D1 (club) baseball player, Colby has been betting since his college days at DePaul, where he had to endure the worst collegiate basketball the Big East has ever seen. He is an advanced analytics nerd and has never seen an underdog he has not liked. Hot. Corn. Bull. It does not matter the dog he loves them all.
This site contains commercial content. We may be compensated for the links provided on this page. The content on this page is for informational purposes only. Betting News makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.
