Manchester City vs. Liverpool Picks and Predictions: FA Cup
Written by: Nate Hornung
Published: Fri Apr 03, 2026, 4:45 pm ET
Read Time: 5 minutes
soccer
Manchester City and Liverpool get our Saturday betting card started bright and early as the two meet at 7:45 a.m. eastern for this FA Cup Quarterfinal matchup at Etihad Stadium. This will be the teams third time meeting this competition season, as City has handled business in the first couple. But could Liverpool find a way to pull off this massive upset on Saturday? It's doubtful, especially when looking at the betting odds, but our soccer analysts still dove in and found their favorite picks in this match.
Check out the best odds on the market at our top online sportsbooks, for tons of picks in different soccer leagues across the world.
Manchester City vs. Liverpool FA Cup Betting Insights
Dominik Szoboszlai scored the last time Liverpool faced Manchester City just two months ago
Let's discuss the first two meetings. Earlier, in November, the two met in this stadium for their first English Premier League contest of the year. Liverpool probably wishes they didn't even show up, but it was basically like they never took the field. Manchester City thumped their visitors by winning 3-0 in shutout fashion. They led 2-0 at the break and got one more later in the second half. City allowed just one shot on frame from their visitors even though they only controlled 48.5% of possession.
The second meeting at Anfield was slightly more competitive, but City still found a way to win. This match was just a couple months ago in early February. We saw a scoreless first 70 minutes before Dominik Szoboszlai found the back of the net in the 74′ minute to give Liverpool the lead, but it didn't last long. Manchester City rallied for an 84′ minute equalizer from Bernardo Silva, and then Erling Haaland sunk a penalty kick in stoppage time to earn three points for his team. Liverpool, once again, managed just four shots on target, compared to seven from the victors.
Will Liverpool finally find a way to win in this third match against Manchester City?
Matchup Information – Manchester City vs. Liverpool – April 4
- Venue & Location: Etihad Stadium (Manchester, England)
- Date: Saturday, April 4, 2026
- Kick Off: 7:45 a.m. Eastern
- Broadcast: ESPN
Manchester City vs. Liverpool Betting Odds
Odds are courtesy of our friends at Lucky Rebel Sportsbook as of April 3, 2026, at 4:13 p.m. eastern. Sign up today and get a $1,250 deposit bonus and 50 slot spins., and start betting at the sportsbook with the most competitive odds in the industry, and a wide variety of unique markets not offered anywhere else.
Moneyline
- Manchester City -139
- Draw +295
- Liverpool +295
Spread
- Manchester City -1 (+135)
- Liverpool +1 (-165
Total
- Over 3 (-115)
- Under 3 (-105)
Manchester City vs. Liverpool FA Cup Picks and Predictions
Can Rayan Cherki and Manchester City advance to the FA Cup Semifinals with a win over Liverpool?
Best Bet: Manchester City ML (-139) Lucky Rebel Sportsbook
I am willing to pay this juice. Manchester City is at home, they are the better team and are in much better form. They sit nine points behind Arsenal with just eight EPL matches remaining, so winning the domestic league might be out of reach, which means they can focus on this FA Cup contest.
It's also worth considering that Manchester City is out of the UEFA Champions League competition after losing to Real Madrid. Liverpool not only has to worry about their UCL contest on Wednesday, but they also have to travel to France to face Paris Saint-Germain. They have much more on their plate, so the focus could be a little shaky going on the road against one of the best teams in the EPL.
Sure, the FA Cup is not as prestigious as the EPL or UCL, but teams will still want to win. And Manchester City can afford to put all their eggs in this basket as they get to wait until next Sunday, April 12 for their next match in the EPL. I do think this match will be low scoring, so pairing City with an inflated under for plus money could be the move, as I am seeing City/Under 4.5 for +138.
Prediction: Manchester City Wins 1-0 (+875)
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Nate has been a recreational sports bettor for about 5 years. In that time, he has grown to love the pursuit of winners and sticking it to The Man. Nate loves data and uses his understanding of numbers to help him be a more profitable sports gambler, however he will be the first to tell you this game is about more than just stats.
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