Can’t Miss Player Props for Week 6 — NFL Expert Picks & Predictions (10/18)
Written by: Varun Sharma
Published: Fri Oct 16, 2026, 7:44 pm ET
Read Time: 5 minutes
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This week's NFL slate looks great. We've got 4 totals in the 50s, good weather across the league and some really good looking matchups to target.
I've got 3 props locked in for this week, let's jump right in and break them down.
For additional information on picks, props, moneylines, and more on today's slate, take a look at our NFL Picks Page or our NFL Odds Page.
Best Bets for Week 5
- Puka Nacua o92.5 Receiving Yards (-114)
- Drake London o92.5 Receiving Yards (-111)
- Jalen Coker o57.5 Receiving Yards (-105)
Puka Nacua should feast against the Bears secondary
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Puka Nacua o92.5 Receiving Yards (-114) | Lucky Rebel
As chalky as this is, as long as Puka's line is below 95 yards; I'm going to bet it. Puka's target share this year and last year just can't be ignored.
Since the start of last year, when Nacua is on the field, he's seeing a 39.2% target share, averaging 0.37 targets per route run and 3.6 yards per route run. He's third in the NFL in target share going back to last season, he accounts for 38% of his team's air yards and he's seeing a 38% 1st read target share.
This Rams' offense runs through Puka and this week they go up against an extremely soft Arizona Cardinals defense. Arizona ranks 25th in pass yards allowed, 28th in opponent yards per play and 25th in pressure rate this year.
The team hasn't done a good job of keeping receivers in front of them and their pass rush has done nothing to help. The Cardinals also run 2-Hi coverages at the 2nd highest rate in the NFL this year and that's a matchup made for Puka.
Puka leads the NFL in targets per route run against 2-Hi, averaging 0.39 TPRR and 3.26 YPRR. He's seen 11+ targets in 3 straight matchups with the Cardinals and this week should be no different.
Drake London o92.5 Receiving Yards (-111) | Lucky Rebel
Drake London and his volume when playing with Michael Penix Jr. just can't be ignored. With Penix on the field this year, London's target share has climed to 33%, he's averaging 0.30 targets per route run and 5.04 yards per route run.
London's been one of the best receivers in the NFL when he's got Penix under center and this week it looks like he'll have his guy out there. London's also been one of the league's best wideouts against man coverage this year and that's something the Bears run a ton of.
Chicago ranks 2nd in man coverage rate this year and we saw them get burned by both Christian Watson and Matthew Golden last week. The Bears rank 5th in points allowed, 12th in passing yards allowed, but 30th in opponent yards per play.
The Bears defense has been propped up by a few good matchups, one really bad weather game and an offense that puts up points. Chicago watched as both Watson and Golden went crazy last week, but it was Week 1 we saw this defense first go to work.
The Bears watched as Bryce Young threw for 361 yards, 3 touchdowns and just 1 interception. Both Jalen Coker and Tetairoa McMillian combined for 213 yards, 2 touchdowns and 13 total catches between the two of them.
Jalen Coker o57.5 Receiving Yards (-105) | Lucky Rebel
Speaking of Jalen Coker, he's finally back. Coker and the Panthers are coming off a bye week and it looks like Coker's back at full health. He was a full participant at practice this week and that's important when you look at the matchup this week.
The Panthers will head to the City of Brotherly Love to take on the beat up Eagles and what's left of this offense. The Eagles rank 2nd last in yards allowed to receivers out of the slot, they've given up 5 touchdowns to the slot and they've just struggled to cover the position in general.
Cooper DeJean is taking all of the Eagles snaps in the slot and he's been bad. He's been targeted 26 times, allowing 17 catches for 206 yards and 3 touchdowns. He's allowing a passer rating of 112.3 when targeted and I don't see why that would change this week.
Coker's taking 45% of his snaps in the slot this year, he's 8th in the NFL in terms of separation this year and 13th in route win rate. He's been elite at all levels this year and the Panthers couldn't be more excited to have him back.
Looking for More
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NFL Week 5 Recap — Early Injury Report & Waiver Wire Adds
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