<p>It may not be getting the same level of attention as a couple of other notable games in the SEC this weekend, the all-maroon matchup between Texas A&amp;M and Mississippi State is very much worth your attention.</p>
<p>Last season, the Bulldogs went into College Station and beat a ranked A&amp;M squad 26-22, delivering the Aggies a second straight loss to open SEC play. </p>
<p>It was MSU’s fifth win in eight seasons against A&amp;M, and even though A&amp;M is ranked in the top 20 and fresh off of a win over a top-ten Arkansas team, Mike Leach’s unranked Bulldogs are favored to make it six wins in nine meetings come Saturday.</p>
<h2 id="ee53d">Texas A&amp;M Aggies vs. Mississippi State Bulldogs Matchup Information and Betting Odds</h2>
<h3 id="at08d">Matchup Information</h3>
<ul>
<li>Matchup: #17 Texas A&amp;M Aggies (3-1, 1-0 SEC) vs. Mississippi State Bulldogs (3-1, 0-1 SEC)</li>
<li>Venue &amp; Location: Davis Wade Stadium at Scott Field (Starkville, Mississippi)</li>
<li>Date: Saturday, October 1, 2022</li>
<li>Game Time: 4:00 p.m. Eastern Time (3:00 p.m. local time)</li>
<li>How to Watch Texas A&amp;M vs. Mississippi State: SEC Network</li>
</ul>
<h3 id="c8kc1">Texas A&amp;M vs. Mississippi State Odds</h3>
<p><strong><em>Game odds are via <a href="https://affiliates.bettingnews.com/register/betonline/" target="_blank" rel="noopener noreferrer">BetOnline</a>. Odds from our other recommended <a href="/legal/" target="_blank" rel="noopener noreferrer">legal sports betting</a> sites may also appear in this article.</em></strong></p>
<h4 id="3ict4">Spread</h4>
<ul>
<li>Texas A&amp;M +3.5 (-110)</li>
<li>Mississippi State -3.5 (-110)</li>
</ul>
<h4 id="3k3p7">Over/Under</h4>
<ul>
<li>Over 44.5 (-115)</li>
<li>Under 44.5 (-105)</li>
</ul>
<h4 id="40tr7">Moneyline</h4>
<ul>
<li>Texas A&amp;M +155</li>
<li>Mississippi State -188</li>
</ul>
<h2 id="691kh">Texas A&amp;M vs. Mississippi State Prediction and Betting Picks</h2>
<p><strong>Texas A&amp;M vs. Mississippi State Prediction:</strong> Mississippi State to win</p>
<p><strong>Texas A&amp;M vs. Mississippi State Picks:</strong> Mississippi State -3.5 (Best Value: -110 at <a href="https://affiliates.bettingnews.com/register/betonline/" target="_blank" rel="noopener noreferrer">BetOnline</a> &amp; <a href="https://affiliates.bettingnews.com/register/bmgm/" target="_blank" rel="noopener noreferrer">BetMGM</a>) &amp; Mississippi State team total over 24.5 points (Best Value: -102 at BetOnline)</p>
<p>Last Saturday, A&amp;M impressively battled back from an early two-touchdown deficit to edge Arkansas 23-21. </p>
<p>The Aggies needed a hefty dose of good fortune to come out on top in Dallas. In the second quarter, they turned an unnecessary and ill-advised leap towards the goal line by Arkansas QB KJ Jefferson into a game-changing scoop, lateral, and score.</p>
<p>Then, with a minute and a half left, a potential go-ahead field goal doinked off the upright to give A&amp;M the win.</p>
<p>Things will need to go a bit differently for the Aggies to win in Starkville this Saturday.</p>
<p>Their defense certainly deserves a lot of credit for holding the Razorbacks to just seven points after they scored two touchdowns in the first nine and a half minutes.</p>
<p>And QB Max Johnson did what he needed to and got some help from RB Devin Achane, who ran for 159 yards on 19 carries.</p>
<p>But for a team with as much talent as Jimbo Fisher has assembled, things are still not clicking nearly well enough to be convinced that they can be counted on to deliver week in, week out. </p>
<p>Mississippi State let a golden opportunity slip away at LSU a couple of weeks ago, and there are going to be nights when Mike Leach-led teams fall flat in games that they could or should win. </p>
<p>But the Bulldogs will be up for this one on both sides of the ball, and they will score yet another win over a ranked Texas A&amp;M team.</p>
<h2 id="ao8ft">More College Football Week 5 Content on Betting News</h2>
<ul>
<li><a href="/articles/ncaaf/utah-state-byu-prediction-picks-september-29-2022/">Utah State vs. BYU Prediction &amp; Best Bets</a></li>
<li><a href="/articles/ncaaf/washington-ucla-prediction-odds-best-bets-ncaaf-week-5/">Washington vs. UCLA Prediction &amp; Best Bets</a></li>
<li><a href="/articles/ncaaf/utsa-middle-tennessee-prediction-picks-09302022/">UTSA vs. Middle Tennessee Prediction &amp; Best Bets</a></li>
<li><a href="/articles/ncaaf/michigan-iowa-prediction-picks-october-1-2022/">Michigan vs. Iowa Prediction &amp; Best Bets</a></li>
<li><a href="/articles/ncaaf/oklahoma-tcu-prediction-picks-october-1-2022/">Oklahoma vs. TCU Prediction &amp; Best Bets</a></li>
</ul>
<p><script>if(window.strchfSettings === undefined) window.strchfSettings = {};window.strchfSettings.stats = {url: "https://betting-news.storychief.io/en/texas-a-m-mississippi-state-prediction-picks-college-football-week-five?id=839109201&type=2",title: "Texas A&amp;M vs. Mississippi State Betting: Will the Bulldogs take a bite out of the Aggies yet again?",id: "4af471aa-0a59-40f0-a023-eeb51e59464b"};(function(d, s, id) {var js, sjs = d.getElementsByTagName(s)[0];if (d.getElementById(id)) {window.strchf.update(); return;}js = d.createElement(s); js.id = id;js.src = "https://d37oebn0w9ir6a.cloudfront.net/scripts/v0/strchf.js";js.async = true;sjs.parentNode.insertBefore(js, sjs);}(document, 'script', 'storychief-jssdk'))</script></p>

Texas A&M vs. Mississippi State Betting: Will the Bulldogs take a bite out of the Aggies yet again? cover

Texas A&M vs. Mississippi State Betting: Will the Bulldogs take a bite out of the Aggies yet again?

Kennesaw State vs. Jacksonville State: Conference USA Championship | December 5, 2025

Dan Mullen led the Rebels to 10 wins in his first season as Head Coach - Boise State UNLV Picks

UNLV vs. Boise State Picks and Predictions: Mountain West Championship

Duke quarterback Darian Mensah - No. 19 Virginia vs. Duke Prediction & Best Bets (11/15/2025)

Duke vs. #17 Virginia: ACC Conference Championship | December 6, 2025

Jeremiah Smith and Ohio State are back in the Big Ten Championship this season - Indiana Ohio State Picks

#2 Indiana vs. #1 Ohio State Picks and Predictions: Big Ten Championship

Jon Sumrall was hired as the next head coach of the Florida Gators - Tulane North Texas Picks

Texas A&M vs. Mississippi State Betting: Will the Bulldogs take a bite out of the Aggies yet again?

Eddie Griffin

More NCAAF News

Kennesaw State vs. Jacksonville State: Conference USA Championship | December 5, 2025

UNLV vs. Boise State Picks and Predictions: Mountain West Championship

Duke vs. #17 Virginia: ACC Conference Championship | December 6, 2025

#2 Indiana vs. #1 Ohio State Picks and Predictions: Big Ten Championship

#24 North Texas vs. #20 Tulane Picks and Predictions: AAC Championship