Los Angeles Chargers vs Buffalo Bills Picks, Odds & Player Props
Highmark Stadium, Orchard Park
Best Odds

Herbert, Harbaugh Take on Buffalo: Chargers vs. Bills – NFL Expert Picks & Predictions (9/27) - Nate Hornung
Consensus Picks
Weather Forecast
Not applicableBN Computer Picks
Projected Winner
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Projected Winner
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Los Angeles Chargers
45.6%
BN Fair Odds
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+119
Moneyline Edge
Predicted Score
21.9
Model Spread
+2.5
Buffalo Bills
54.4%
More information
BN Fair Odds
-119
Moneyline Edge
Predicted Score
24.4
Model Spread
-2.5
LAC (Away)vsBUF (Home)
Pass Offense
Pass Defense
Rush Offense
Rush Defense
NFL ratings compare each team's passing and rushing offense and defense. Ratings are percentile-based from 0–100.
Betting Records
LAC
BUF
1 - 6(30th)
1 - 2
Wins
Away/Home
(2nd)6 - 1
3 - 1
2 - 4 - 1(28th)
1 - 1 - 1
ATS
Away/Home
(1st)6 - 1 - 0
3 - 1 - 0
2 - 4 - 1(29th)
1 - 1 - 1
Ov / Un
Away/Home
(1st)5 - 1 - 1
2 - 1 - 1
Offensive Stats
LAC
BUF
Defensive Stats
LAC
BUF
Last 5 Games
LAC
Result
ATS
Total
vs DEN
L23 - 17
L+3.5
42
@ SEA
L23 - 30
P+7.0
42
@ BUF
L16 - 24
L+7.0
50
vs LV
L26 - 14
L-6.5
43
vs ARI
L26 - 14
L-9.5
47
BUF
Result
ATS
Total
@ LAR
W37 - 34
W+1.5
-
vs NE
L29 - 26
L-7.0
50
vs LAC
W16 - 24
W-7.0
50
vs DET
W31 - 41
W-5.5
P72
@ HOU
W36 - 31
W-1.5
44