Week 7 Saturday Best Bets: NCAA Football Expert Picks & Predictions (10/17)

Written by: Nate Hornung
Published: Fri Oct 16, 2026, 6:00 pm ET
Read Time: 5 minutes

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Spread
Total
Moneyline
+11.5
-110
51
-108u
+345
Spread
Total
Moneyline
-11.0
-110
51
-110o
-420
We are nearing the halfway point in the college football season, so everyone take a second and appreciate the glorious slate we have upon us. Six different ranked on ranked matchups perfectly spread out throughout the day. Park your butt on the couch for 14 hours, and check out our NCAA Football expert picks for this Saturday's action below.
Check out the best odds on the market and tons of picks for the NCAA Football Season.
NCAA Football Saturday's Predictions – October 17
#4 Ohio State vs. #5 Indiana NCAA Football Picks
Best Bet: Ohio State Team Total Over 27.5 (-115) BetOnline
Despite these two teams playing to a 13-10 Big Ten Championship last year, I think the Buckeyes offense is even more dangerous this season. They've scored 56, 59, 42, 31 and 45 points this season. Sure, they only managed 23 against the Longhorns in that loss, but they did that in just two and a half quarters.
Indiana's defense is not what they were last season, as we saw with the Northwestern Wildcats scoring 23 in their trip to Bloomington. Ohio State is capable of four touchdowns to assert their dominance in the conference.
Florida vs. #7 Texas NCAA Football Picks
Best Bet: Florida +11.5 (-112) BetOnline
Nobody wants any part of Florida right now after two straight losses. Aaron Philo might not even play and now they face Texas coming off a loss. I think they have the ability to keep this low scoring, much like the Sooners did, and cover a big number.
Of course I'll be rooting for the Gators outright with my Texas win total under ticket, but keeping it within double digits is all we need. The Longhorns offense struggled to get anything explosive going against Oklahoma, and even at home I see that continuing… cause Arch just ain't it. Florida on their backup QB isn't a huge step back, as Tramell Jones Jr. is plenty capable of handing the ball off and letting Jadan Baugh run wild.
A Moneyline Parlay to Keep Your Attention

Back Ole Miss at home this weekend, and pair their ML with Oklahoma for an SEC ML Parlay
Best Bet: Ole Miss/Oklahoma ML Parlay (+107) BetOnline
Who wants some fun? We have a couple of SEC home favorites to get the job done this Saturday as over a field goal favorite. Don't overthink this.
Kentucky is coming off a huge win over LSU. Sure, the same could be said about the Sooners and Texas, but we also have an unranked home favorite against a ranked opponent. They are favored for a reason, defense wins this game, and the Sooners have the edge. As for the Rebels, they host the Missouri Tigers, who I am still doubting. Yes, they beat up on Florida, but any win over Texas A&M is unimpressive at this point. Mizzou already lost once on the road in the SEC, and this weekend we'll see they aren't the same as the team who plays in Columbia.
Kansas vs Kansas State NCAA Football Picks
24 Hours ⏳
#EMAW https://t.co/eaQxRAXOrR
— K-State Football (@KStateFB) October 16, 2026
Best Bet: Kansas State -3.5 (-110) BetOnline
As a Kansas guy, I have to talk about the Sunflower Showdown.
We bet Kansas State last week and they didn't show up. They looked terrible. Now they have suffered two straight conference losses, their season is over, but this is perfect spot for them to unleash their wrath, in a rivalry game against "Little Brother".
Let's be honest, folks, at this point, this is the Wildcats' Super Bowl, and for some reason the spread has been bet down from 5.5 to 3.5. I've got to take it at this point. Sorry, Jayhawks fans, see you for basketball season.
#6 Alabama vs. #14 Tennessee NCAA Football Picks
Best Bet: Alabama/Tennessee Under 52.5 (-116) BetOnline
Yes, this sicko is backing the under in a game involving the Crimson Tide, the highest scoring offense in the nation. However, they are on the road in a hostile environment, where they've lost two straight. This Tennessee defense is top 15 in yards per play allowed and top 16 in points per game allowed this season.
When Texas came to Knoxville with about this spread, the Volunteers covered, despite QB issues, in a low scoring game. I expect them to lean on the defensive side of the ball to keep this game close, and ultimately the Tide's defense will play up as needed. Give me a slugfest.
#2 Notre Dame vs. #8 BYU NCAA Football Picks
Best Bet: Notre Dame -10.5 (-110) BetOnline
Notre Dame by murder. End of handicap. Read more here.
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Nate has been a recreational sports bettor for about 5 years. In that time, he has grown to love the pursuit of winners and sticking it to The Man. Nate loves data and uses his understanding of numbers to help him be a more profitable sports gambler, however he will be the first to tell you this game is about more than just stats.
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