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Tennessee Titans vs Indianapolis Colts Picks

Lucas Oil Stadium

<p>After getting into the win column for the first time this season, the Tennessee Titans and Indianapolis Colts will renew their rivalry on Sunday at Lucas Oil Stadium.</p>
<p>Tennessee held a 24-10 lead over the Las Vegas Raiders at halftime but failed to score in the second half, but they survived with a 24-22 win thanks to stopping the Raiders’ game-tying two-point conversion attempt.</p>
<p>While Tennessee had to hold on for dear life, the Colts rode some good fortune and some much-needed clutch plays to rally and pick up a 20-17 win over Patrick Mahomes and the Kansas City Chiefs.</p>
<p>For now, both of these teams are looking up at the Jacksonville Jaguars in the AFC South standings, but with the Jaguars facing a tough trip to Philadelphia in Week 4, the winner of this game could be in a better position Sunday evening.</p>
<h2 id="fliaq">Tennessee Titans vs. Indianapolis Colts Matchup Information and Betting Odds</h2>
<h3 id="9gff">Matchup Information</h3>
<ul>
<li>Matchup: Tennessee Titan (1-2, 0-1 away, 3rd in the AFC South) vs. Indianapolis Colts (1-1-1, 1-0 home, 2nd in the AFC Central)</li>
<li>Venue &amp; Lucas Oil Stadium (Indianapolis, Indiana)</li>
<li>Date: Sunday, October 2, 2022</li>
<li>Game Time: 1:00 p.m. Eastern Time</li>
<li>How to Watch Titans vs. Colts: FOX</li>
</ul>
<h3 id="a606f">Titans vs. Colts Odds</h3>
<p><strong><em>Game odds are via <a href="https://affiliates.bettingnews.com/register/betonline/" target="_blank" rel="noopener noreferrer">BetOnline</a>. Odds from our other <a href="/best-online-sportsbooks/" target="_blank" rel="noopener noreferrer">recommended legal sports betting sites</a> may also appear in this article. </em></strong></p>
<h4 id="anm0p">Spread</h4>
<ul>
<li>Tennessee Titans +3 (-102)</li>
<li>Indianapolis Colts -3 (-120)</li>
</ul>
<h4 id="3adh4">Over/Under</h4>
<ul>
<li>Over 43 (-110)</li>
<li>Under 43 (-110)</li>
</ul>
<h4 id="3hrth">Moneyline</h4>
<ul>
<li>Tennessee Titans +148</li>
<li>Indianapolis Colts -174</li>
</ul>
<h2 id="73cvr">Tennessee Titans vs. Indianapolis Colts Prediction and Best Bets</h2>
<p><strong>Titans vs. Colts Prediction:</strong> Tennessee to win</p>
<p><strong>Titans vs. Colts Best Bets:</strong> Tennessee +3.5 (Best Value: -110 at <a href="https://affiliates.bettingnews.com/register/bmgm/" target="_blank" rel="noopener noreferrer">BetMGM</a>) &amp; Tennessee ML (Best Value: +150 at <a href="https://affiliates.bettingnews.com/register/betus/" target="_blank" rel="noopener noreferrer">BetUS</a> &amp; BetMGM)</p>
<p>The Titans have made themselves at home at Lucas Oil Stadium in recent years, winning each of the last three meetings there. </p>
<ul>
<li>2021: Tennessee 34, Indianapolis 31 (OT)</li>
<li>2020: Tennessee 45, Indianapolis 26</li>
<li>2019: Tennessee 31, Indianapolis 37</li>
<li>2018: Indianapolis 38, Tennessee 10</li>
<li>2017: Tennessee 20, Indianapolis 16</li>
</ul>
<p>Look for them to make it four in a row and five of six on Sunday. The Colts certainly did well to come from behind and take down the Chiefs last week, but they didn’t really do enough to make me want to trust them in this spot.</p>
<p>Derrick Henry has had a couple of big games in Indianapolis, and I’m high on his prospects for Sunday. </p>
<p>Henry has yet to reach 100 yards on the ground this season, and you know it is only a matter of time before he does. After totaling 143 yards on 26 touches against the Raiders (85 yards rushing on 21 carries, 58 yards receiving on five catches), he is on the cusp.</p>
<p>Also, after having his regular season ended last year in Indianapolis, he might be feeling a little extra inspired for this matchup. So, in addition to backing Tennessee get the rivalry win, this week will be a good week to hit the Henry props hard.</p>
<h2 id="fkcjt">More Titans vs. Colts Content on Betting News</h2>
<ul>
<li><a href="/nfl/matchup/2022-10-02-tennessee_titans-indianapolis_colts-n-1/">Titans vs. Colts Consensus Picks, Score Projections &amp; Betting Stats</a></li>
</ul>
<h2 id="93jva">More NFL Week 4 Content on Betting News</h2>
<ul>
<li><a href="/articles/nfl/dolphins-bengals-odds-prediction-best-bets-nfl-week-4-tnf/">Dolphins vs. Bengals Prediction &amp; Picks</a></li>
<li><a href="/articles/nfl/vikings-saints-prediction-odds-best-bets-nfl-london-week-4/">Vikings vs. Saints Prediction and Best Bets</a></li>
<li><a href="/articles/nfl/bills-ravens-prediction-odds-best-bets-nfl-week-4/">Bills vs. Ravens Prediction &amp; Best Bets</a></li>
</ul>
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Titans vs. Colts Week 4 Betting: Will Tennessee make it four straight wins in Indy? cover

Titans vs. Colts Week 4 Betting: Will Tennessee make it four straight wins in Indy?

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