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Los Angeles Chargers vs San Francisco 49ers Picks

Levi's Stadium

<p>Some of the top talents in the NFL will be on display in prime time on Sunday night, as the Week 10 Sunday Night Football matchup will see the Los Angeles Chargers take on San Francisco 49ers at Levi’s Stadium.</p>
<p>Justin Herbert and the Chargers are behind Patrick Mahomes and the Kansas City Chiefs in the AFC West, but they are 5-3 after returning from their bye week with a 20-17 road win over the Atlanta Falcons.</p>
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<p lang="en" dir="ltr">DICKER THE KICKER!!<br />DICKER THE KICKER!!!<br />DICKER THE KICKER!!!! <a href="https://t.co/AxlChjvmND">pic.twitter.com/AxlChjvmND</a></p>
<p>&mdash; Los Angeles Chargers (@chargers) <a href="https://twitter.com/chargers/status/1589373193017606145?ref_src=twsrc%5Etfw">November 6, 2022</a></p></blockquote>
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<p>The Chargers are behind the Bills, Chiefs, Ravens, Dolphins, and Bengals among the favorites in the AFC, but a win on Sunday would serve to enhance their credentials as a championship contender.</p>
<p>The Niners, who had their bye week last week, are only 4-4 and looking up at the 6-3 Seattle Seahawks in the NFC West. </p>
<p>But after trading for Christian McCaffrey and evening their record with a big win over the Rams in Week 8, they are currently the second favorite for the NFC title, behind only the 8-0 Philadelphia Eagles.</p>
<p>It might seem a little strange to see a 4-4 team in that spot, but they are highly thought of even after some early struggles and enter this matchup firmly favored to complete the regular season sweep of teams that play at SoFi Stadium.</p>
<h2 id="6o72e">Los Angeles Chargers vs. San Francisco 49ers Matchup Information</h2>
<ul>
<li>Matchup: Los Angeles Chargers (5-3, 3-1 away, 2nd in the AFC West) vs. San Francisco 49ers (4-4, 2-1 home, 2nd in the NFC West)</li>
<li>Venue &amp; Location: Levi’s Stadium (Santa Clara, California)</li>
<li>Date: Sunday, November 13, 2022</li>
<li>Game Time: 8:20 p.m. Eastern Time (5:20 p.m. local time)</li>
<li>How to Watch Chargers vs. 49ers: NBC &amp; Peacock</li>
</ul>
<h2 id="1vllm">Los Angeles Chargers vs. San Francisco 49ers Early Odds</h2>
<p><strong><em>Game odds are via <a href="https://affiliates.bettingnews.com/register/betonline/" target="_blank" rel="noopener noreferrer">BetOnline</a> as of Tuesday, November 8 at 11:50 a.m. Eastern.</em></strong></p>
<h3 id="9pg6j">Spread</h3>
<ul>
<li>Los Angeles Chargers +7 (-110)</li>
<li>San Francisco 49ers -7 (-110)</li>
</ul>
<h3 id="4t0a6">Over/Under</h3>
<ul>
<li>Over 46.5 (-110)</li>
<li>Under 46.5 (-110)</li>
</ul>
<h3 id="1g2od">Moneyline</h3>
<ul>
<li>Los Angeles Chargers +245</li>
<li>San Francisco 49ers -300</li>
</ul>
<h2 id="4ur31">Will a Major Defensive Concern Burn the Bolts?</h2>
<p>A win is a win is a win in the NFL, no matter how it happens, but the Chargers were certainly fortunate to leave Atlanta with a win. </p>
<p>They used long drives to score touchdowns on their last two possessions of the first half, but Herbert and the offense continue to underwhelm relative to preseason expectations. </p>
<p>On defense, the Falcons were able to stay in the game the entire way due to a rushing attack that produced 201 yards on 35 carries (5.7 yards per carry). </p>
<p>It was the second straight game and third time this season&#8211;all in their last four games&#8211;in which the Chargers allowed 200+ rushing yards. Against the Seahawks in a Week 7 loss, they allowed 213 yards on 34 carries (6.3 yards per carry), and they gave up 213 on 31 carries (6.9 yards per carry) against the Browns in a Week 5 win. </p>
<p>For the season, the Chargers rank last in the NFL in yards allowed per carry (5.7) and 29th in rushing yards allowed per game (145.5). </p>
<p>That spells some serious trouble against McCaffrey, who has averaged 5.1 yards per carry (132 yards on 26 carries) in two games with his new team. </p>
<p>In San Francisco’s 31-14 road win over the Rams in Week 8, he tallied 149 rushing + receiving yards (94 rushing on 18 carries and 55 receiving on eight catches) and accounted for three touchdowns (one rushing, one receiving, and one passing).</p>
<h2 id="6r5nq">Los Angeles Chargers vs. San Francisco 49ers Prediction</h2>
<h3 id="7ef77">49ers to win</h3>
<p>While the Niners should flourish on the ground, the Chargers will be going up against the NFL’s best run defense. San Francisco is first in the league in both yards allowed per carry (3.4) and yards allowed per game (86.6).</p>
<p>Were Herbert playing much better, I might have a little more faith in the Chargers to be productive on offense even if they don’t generate much on the ground. </p>
<p>But over his last three games, Herbert has averaged just 5.1 yards per attempt, and he is averaging just 6.4 yards per attempt this season after averaging 8.2 yards per attempt in the season opener against the Raiders.</p>
<p>If they play up to their true potential, the Chargers could challenge for the upset. But I haven’t seen that potential enough from them this season to be confident that they can do that against a team that can exploit their weaknesses well.</p>
<h2 id="89v3d">Los Angeles Chargers vs. San Francisco 49ers Best Bets</h2>
<ul>
<li>49ers to cover (Best Value: over 46 @ -110 at <a href="https://affiliates.bettingnews.com/register/bovada/" target="_blank" rel="noopener noreferrer">Bovada Sportsbook</a>)</li>
<li>49ers team total over (Best Value: over 27 @ -112 at <a href="https://affiliates.bettingnews.com/register/betonline/" target="_blank" rel="noopener noreferrer">BetOnline</a>)</li>
</ul>
<h2 id="dg1qb">More Los Angeles Chargers vs. San Francisco 49ers Content on Betting News</h2>
<ul>
<li><a href="/nfl/matchup/2022-11-13-los_angeles_chargers-san_francisco_49ers-n-1/">Chargers vs. 49ers SNF Consensus Picks, Score Projections &amp; Betting Stats</a></li>
</ul>
<h2 id="2g0me">Other NFL Week 10 Stories on Betting News</h2>
<ul>
<li><a href="/articles/nfl/week-ten-thursday-night-football-falcons-panthers-prediction-odds-picks/">Falcons vs. Panthers Prediction &amp; Best Bets (Week 10 Thursday Night Football)</a></li>
<li><a href="/articles/nfl/seahawks-buccaneers-prediction-odds-best-bets-nfl-week-10/">Seahawks vs. Buccaneers Betting (Munich)</a></li>
<li><a href="/articles/nfl/cowboys-packers-prediction-odds-best-bets-nfl-week-10/">Cowboys vs. Packers Week 10 Betting: Green Bay’s Slump Continues Against Dallas</a></li>
<li><a href="/articles/nfl/vikings-bills-prediction-odds-best-bets-week-10-november-13-2022/">Vikings vs. Bills Prediction &amp; Best Bets</a></li>
<li><a href="/articles/nfl/broncos-vs-titans-prediction-week-10/">Broncos vs. Titans Prediction &amp; Best Bets</a></li>
<li><a href="/articles/nfl/colts-vs-raiders-prediction-week-10/">Colts vs. Raiders Prediction &amp; Best Bets</a></li>
<li><a href="/articles/nfl/browns-dolphins-prediction-odds-best-bets-nfl-week-10/">Browns vs. Dolphins Prediction &amp; Best Bets</a></li>
<li><a href="/articles/nfl/saints-vs-steelers-nfl-prediction-week-10/">Saints vs. Steelers Prediction &amp; Best Bets</a></li>
<li><a href="/articles/nfl/lions-bears-prediction-odds-best-bets-2022-nfl-week-10/">Lions vs. Bears Prediction &amp; Best Bets</a></li>
<li><a href="/articles/nfl/cardinals-rams-odds-prediction-best-bets-2022-nfl-week-10/">Cardinals vs. Rams Prediction &amp; Best Bets</a></li>
<li><a href="/articles/nfl/commanders-eagles-prediction-odds-picks-2022-nfl-week-10-mnf/">Commanders vs. Eagles Prediction &amp; Best Bets (Week 10 Monday Night Football)</a></li>
</ul>
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Chargers vs. 49ers (Week 10 Sunday Night Football): Will the Niners Run Wild at Home? cover

Chargers vs. 49ers (Week 10 Sunday Night Football): Will the Niners Run Wild at Home?

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