Dimers

Dratings

DunkelIndex

OddsShark

SportGrid

Sports Betting Dime

Moneyline

Total

Point Spread

Away/Home

Wins

Ov / Un

Raiders

Chargers

Away/Home Defense

Away/Home Offense

Defense

Offense

Las Vegas Raiders vs Los Angeles Chargers Picks

SoFi Stadium

<p>The AFC West is loaded this season, and we get to see two of the teams face off against each other in the first week of the season. The Las Vegas Raiders will travel to Los Angeles to face off against the Chargers.</p>
<p>The Raiders were one of the two teams from the AFC West to make the playoffs last season. With a 10-7 record, they made it into the Wild Card round. They had a quick exit, as Cincinnati knocked them out for their first playoff win in 31 years.</p>
<p>The Chargers were a field goal away from the playoffs. In their Week 18 game against the Raiders last year, they needed the game to finish in a tie once it got to overtime. Unfortunately for them, the Raiders kicked a field goal as time expired in the extra session, and they missed out on the postseason.</p>
<p>According to <a href="https://sportsbook.fanduel.com/football?tab=nfl-week-1">BetOnline</a>, the Chargers are 3.5 point favorites on Sunday. However, with the addition of DaVante Adams for the Raiders, it will be a good matchup for Derek Carr and the Raiders’ offense.</p>
<h2 id="cj2im">Las Vegas Raiders vs. Los Angeles Chargers Week 1 Matchup Information and Betting Odds</h2>
<h3 id="7e8mb">Matchup Information</h3>
<ul>
<li>Matchup: Las Vegas Raiders (0-0) vs. Los Angeles Chargers (0-0)</li>
<li>Venue &amp; Location: SoFi Stadium (Inglewood, California)</li>
<li>Date: Sunday, September 11, 2022</li>
<li>Game Time: 4:25 p.m. Eastern Time</li>
<li>Raiders vs. Chargers TV Info: CBS</li>
</ul>
<h3 id="1cae">Raiders vs. Chargers Odds</h3>
<p><strong><em>Game odds are via <a href="https://affiliates.bettingnews.com/register/betonline/">BetOnline</a>. Odds from other <a href="/best-online-sportsbooks/">top online sportsbooks</a> may also be mentioned in this article.</em></strong></p>
<h4 id="8s67d">Spread</h4>
<ul>
<li>Las Vegas Raiders +3.5 (-118)</li>
<li>Los Angeles Chargers -3.5 (-104)</li>
</ul>
<h4 id="fq0n0">Over/Under</h4>
<ul>
<li>Over 52.5 (-106)</li>
<li>Under 52.5 (-114)</li>
</ul>
<h4 id="6t0nv">Moneyline</h4>
<ul>
<li>Las Vegas Raiders +154</li>
<li>Los Angeles Chargers -184</li>
</ul>
<h2 id="bq34f">The Charger Defense</h2>
<p>Last season, the Chargers were not lighting it up in the major defensive categories. They were ranked 29th in total defense, and they gave up a lot of points (tied for 22nd in the NFL).</p>
<p>They were especially bad against the run. They allowed the 3rd most rushing yards in the league and the 4th most touchdowns on the ground.</p>
<p>The one thing they weren’t at the bottom of the NFL in was defending the deep pass. They were 12th in the NFL against the pass, but they were still giving up touchdowns through the air.</p>
<p>When a team is dead last in 3rd down percentage, that means they are not getting teams off the field quick enough. The Chargers were in that sad position in 2021. With the Raiders improving their offense this offseason, they will need major improvement.</p>
<p>The Raiders were the 6th best team in the offensive passing game last season, and that was without DaVante Adams on the team. The sky&#x27;s the ceiling for that offense, and the Chargers are going to have to learn to defend all 3 other AFC West passing attacks.</p>
<p>I see Los Angeles wearing themselves out quickly in a game like this. It could be a shootout with two prolific passing games. Defense will be at a premium, and the Over is definitely in play this weekend.</p>
<h2 id="8ah82">Raiders vs. Chargers Betting Trends</h2>
<ul>
<li>Las Vegas is 6-1 in their last 7 games played in September</li>
<li>LA Chargers are 6-3 in their last 9 games played on a Sunday at home</li>
<li>LA Chargers are 6-4 in their last 10 games against Las Vegas</li>
<li>LA Chargers are 2-7 ATS in their last 9 games against AFC opponents</li>
<li>Las Vegas are 4-2 in their last 6 games against AFC opponents</li>
</ul>
<h2 id="7100b">Las Vegas Raiders vs. Los Angeles Chargers Prediction and Picks</h2>
<p><strong>Raiders vs. Chargers Prediction:</strong> Raiders 35, Chargers 31</p>
<p><strong>Raiders vs. Chargers Picks: </strong>Over 52.5 total points (-106 at <a href="https://sportsbook.fanduel.com/football/nfl/las-vegas-raiders-@-los-angeles-chargers-31451321">BetOnline</a>)</p>
<p>I see a shootout with two Top 5 passing offenses facing off against each other. Both teams struggled against the deeper passing game last season, so there is an added element of big plays in the air.</p>
<p>Lots of people see a major improvement to both defenses, and I just don’t see it happening in Week 1. It might come into play later on in the year, but with a close race in the AFC West, this game should be wild.</p>
<p>Take the Over if you are looking to bet, as it is considered the best value bet of the two. Expect DaVante Adams to have an immediate impact in Week 1, as Derek Carr will have a field day against a struggling secondary for the Chargers.</p>
<h2 id="90ggv">Other NFL Week 1 Stories on Betting News</h2>
<ul>
<li><a href="/articles/nfl/nfl-week-1-predictions-odds-spread-over-under-picks/">NFL Week 1 Predictions, Odds, Spread &amp; Over/Under Picks</a></li>
<li><a href="/articles/nfl/2022-steelers-vs-bengals-week1-predictions-odds-best-bets/">Steelers vs. Bengals Prediction, Odds &amp; Picks for Week 1: Teams Meet in 1st Week for the First Time in History</a></li>
<li><a href="/articles/nfl/2022-browns-vs-panthers-week1-predictions-odds-best-bets/">Browns vs. Panthers Prediction, Odds &amp; Picks for Week 1: Mayfield Makes First Start With New Team Against Former Team</a></li>
<li><a href="/articles/nfl/2022-patriots-vs-dolphins-week1-predictions-odds-best-bets/">Patriots vs. Dolphins Predictions, Odds &amp; Picks for Week 1: Will Tua Lead the Phins to Victory?</a></li>
<li><a href="/articles/nfl/bucs-cowboys-odds-prediction-best-bets-week-1/">Bucs vs. Cowboys Week 1 Betting: Two Top NFC Teams Engage in Sunday Night Showdown</a></li>
<li><a href="/articles/nfl/broncos-seahawks-odds-prediction-best-bets-week-1/">Broncos vs. Seahawks Week 1 Betting: What to Expect in Russell Wilson’s Return to Seattle</a></li>
<li><a href="/articles/nfl/2022-packers-vs-vikings-week1-predictions-odds-best-bets/">Packers vs. Vikings Week 1 Betting: Can Rodgers Be Effective Without Adams?</a></li>
</ul>
<p><script>if(window.strchfSettings === undefined) window.strchfSettings = {};window.strchfSettings.stats = {url: "https://betting-news.storychief.io/en/2022-raiders-vs-chargers-week1-predictions-odds-best-bets?id=2112381525&type=2",title: "Raiders vs. Chargers Week 1 Betting: Loaded AFC West Gets Big Matchup in First Week",id: "4af471aa-0a59-40f0-a023-eeb51e59464b"};(function(d, s, id) {var js, sjs = d.getElementsByTagName(s)[0];if (d.getElementById(id)) {window.strchf.update(); return;}js = d.createElement(s); js.id = id;js.src = "https://d37oebn0w9ir6a.cloudfront.net/scripts/v0/strchf.js";js.async = true;sjs.parentNode.insertBefore(js, sjs);}(document, 'script', 'storychief-jssdk'))</script></p>

Raiders vs. Chargers Week 1 Betting: Loaded AFC West Gets Big Matchup in First Week cover

Raiders vs. Chargers Week 1 Betting: Loaded AFC West Gets Big Matchup in First Week

The top spot in the AFC North is up for grabs. Here's what you should expect in our Baltimore Ravens vs Pittsburgh Steelers preview & picks.

Baltimore Ravens vs Pittsburgh Steelers Preview & Predictions (11/7) | Knockin’ for the North

Get ready for this huge AFC showdown with our Buffalo Bills vs Cincinnati Bengals preview and picks in NFL Week 14.

Buffalo Bills vs Cincinnati Bengals Preview & Picks (12/7): Will Burrow get Buried?

Get all the info and action you need with our Detroit Lions vs Dallas Cowboys Thursday Night Football preview and picks.

Detroit Lions vs Dallas Cowboys Thursday Night Football Preview & Picks (12/4)

Giants vs. Patriots | NFL Week 13 Breakdown & Best Bets: Monday Night @ Foxborough

2025 NFL MVP Odds Update | December 1, 2025