<p>Since the women’s NCAA Tournament bracket was released on March 17, many have been looking forward to a potential Albany 2 regional final between LSU and Iowa, a rematch of last season’s national championship game.</p>
<p>Well, the Tigers and Hawkeyes both did their part, and the most anticipated matchup of the tournament—and perhaps the season—is here. Tonight, Angel Reese and third-seeded LSU (31-5) will meet Caitlin Clark and #1 seed Iowa (32-4) for a place in the Final Four.</p>
<p>Last April, Iowa entered the national championship game in Dallas favored to win after a stunning upset of double-digit favorite South Carolina in the national semifinals.</p>
<p>But Reese and the Tigers played spoiler, downing the Hawkeyes 102-85 to win the program’s first national title.</p>
<p>As was the case then, Iowa is favored for the rematch. The Hawkeyes won their first three NCAA Tournament games by double digits and clobbered #5 Colorado by 21 in the Sweet Sixteen on Saturday.</p>
<p>LSU, meanwhile, is coming off a tense 78-69 win over #2 UCLA. The Bruins led by three late with under three minutes remaining, but the Tigers outscored them 14-2 the rest of the way to move on to the Elite Eight for the tenth time in program history.</p>
<p>Will Clark’s stellar collegiate career end in Albany? Or will she carry the Hawkeyes into a Final Four showdown with either Paige Bueckers or JuJu Watkins?</p>
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<h2>LSU vs Iowa Odds</h2>
<p><strong><em>Odds are via <a href="https://affiliates.bettingnews.com/register/betonline/" target="_blank" rel="noopener sponsored">BetOnline</a>, a longtime fixture in the sports betting industry. Check out our <a href="/best-online-sportsbooks/betonline/" target="_blank" rel="noopener sponsored">BetOnline sportsbook review</a>, then grab yourself a nice sign-up bonus to bet on the men’s and women’s NCAA Tournaments.</em></strong></p>
<h3>Spread</h3>
<ul>
<li>LSU +2.5 (-115)</li>
<li>Iowa -2.5 (-105)</li>
</ul>
<h3>Over/Under</h3>
<ul>
<li>Over 168 (-115)</li>
<li>Under 168 (-105)</li>
</ul>
<h3>Moneyline</h3>
<ul>
<li>LSU +110</li>
<li>Iowa -130</li>
</ul>
<p><strong><em>Looking for more college basketball picks? Our <a href="/ncaab/picks/">NCAA basketball picks</a> page features moneyline, spread, and total (over/under) picks for the NIT semifinals.</em></strong></p>
<h2>LSU vs Iowa Prediction &amp; Picks</h2>
<p>While the Hawkeyes’ lone challenge in the NCAA Tournament came in the second round against West Virginia, the Tigers have been challenged to some level in each of their games thus far.</p>
<p>In a 70-60 win in the first round against #14 Rice, LSU led by only two points midway through the third quarter.</p>
<p>In the second round against #11 Middle Tennessee, LSU trailed by four at halftime and fell behind by nine within the first 75 seconds of the third quarter. From there, the Tigers outscored the Blue Raiders 51-15 to win 83-56.</p>
<p>Then, in the Sweet Sixteen, UCLA erased a seven-point halftime deficit and led for much of the fourth quarter before LSU’s late rally.</p>
<h3>LSU vs Iowa Players to Watch</h3>
<h4>LSU</h4>
<ul>
<li>Angel Reese: 18.7 PPG, 13.2 RPG, 2.3 APG, 1.9 SPG</li>
<li>Aneesah Morrow: 16.5 PPG, 9.9 RPG, 2.6 SPG, 1.7 APG, 1.2 BPG</li>
<li>Flau’jae Johnson: 14.7 PPG, 5.5 RPG, 2.5 APG, 2.1 SPG</li>
<li>Mikaylah Williams: 14.4 PPG, 4.8 RPG, 2.9 APG, 1.2 SPG</li>
<li>Hailey Van Lith: 11.7 PPG, 3.7 APG, 2.5 RPG, 1.3 SPG</li>
</ul>
<h4>Iowa</h4>
<ul>
<li>Caitlin Clark: 31.7 PPG, 8.9 APG, 7.3 RPG, 1.8 SPG</li>
<li>Hannah Stuelke: 14.0 PPG, 6.8 RPG, 62.6% FG</li>
<li>Kate Martin: 12.8 PPG, 6.8 RPG, 2.4 APG</li>
<li>Sydney Affolter: 8.1 PPG, 6.6 RPG, 2.3 APG</li>
<li>Gabbie Marshall: 6.2 PPG, 1.7 APG</li>
</ul>
<p>Should that be cause for concern ahead of their matchup with Iowa?</p>
<p>Were the Tigers almost any other team—save for South Carolina and perhaps Iowa—there would be reason for concern.</p>
<p>But in following women’s college basketball for a long time—I won’t reveal how long, because I would age myself a bit—there are a few things I don’t question.</p>
<p>One of those is the mental fortitude of a Kim Mulkey-coached team, especially in this situation. And that is why I fully expect LSU to win.</p>
<p>Playing for a trip to the Final Four is plenty of reason to be motivated, but between the hope, hype, and expectation surrounding Iowa, the recent storylines surrounding Mulkey and her team, and all of the storylines and pieces of bulletin board material that have been collected along the way in a season that has not been a perfect ride for LSU, a pregame speech for the ages might be on the horizon tonight.</p>
<p>Is it them against the world? Not at all, but I expect them to play like it, much like they did last April.</p>
<p><strong>LSU vs Iowa Prediction:</strong> LSU to cover and win</p>
<p><strong>LSU vs Iowa Betting Picks:</strong> LSU +2.5 &amp; LSU/Iowa over 168</p>
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<h2>More March Madness Betting Information</h2>
<h3>Where Can You Bet on March Madness This Year?</h3>
<p>Each year, millions upon of millions of March Madness bets are placed at the top <a href="/best-online-sportsbooks/">online sports betting sites</a>.</p>
<p>Most March Madness betting takes place around and at tournament time, which is from mid-March to early April. But throughout the year, you can bet on who you think will win the college basketball national championship.</p>
<p>Along with men’s college basketball odds, most good sportsbooks now carry <a href="/articles/ncaab/womens-march-madness-winner-odds-bracket/">women’s college basketball national championship odds</a>. Those odds are drawing a lot of attention with the likes of South Carolina, Iowa, and LSU vying to cut down the nets in Cleveland, Ohio on April 7.</p>
<p>Numerous sportsbooks are good for March Madness betting, but in addition to BetOnline, here are some of the books that we have reviewed and highly recommend:</p>
<ul>
<li><a href="/best-online-sportsbooks/betdsi/" target="_blank" rel="noopener sponsored">BetDSI (Review)</a></li>
<li><a href="/best-online-sportsbooks/betus/" target="_blank" rel="noopener sponsored">BetUS (Review)</a></li>
<li><a href="/best-online-sportsbooks/bovada/" target="_blank" rel="noopener sponsored">Bovada (Review)</a></li>
<li><a href="/best-online-sportsbooks/mybookie/" target="_blank" rel="noopener sponsored">MyBookie (Review)</a></li>
</ul>
<p>If you are unfamiliar with any of the above sites, check out our <a href="/sportsbooks">sportsbook reviews</a> to learn more about them. Speaking of offers, keep an eye on the latest <a href="/offers/">sportsbook offers</a> from these books and others as the countdown to the opening tip of March Madness continues. That way, you will not miss out on any special sports betting promos and bonuses to pad your bankroll for March Madness betting.</p>
<h3>Other March Madness Content at Betting News</h3>
<p>If you like this LSU vs Iowa women’s basketball betting breakdown and would like to check out our other March Madness content, our <a href="/march-madness/">March Madness guide</a> is where you can find it all in one tidy place. But here’s a rundown of some of what we have put together to help you with your NCAA Tournament betting this year.</p>
<p>We’re also covering the <a href="/articles/ncaab/nit-bracket-odds/">2024 NIT</a>, so check out that content as well.</p>
<ul>
<li><a href="/articles/ncaab/march-madness-odds/" target="_self" rel="noopener">Men’s March Madness Futures Odds</a></li>
<li><a href="/articles/ncaab/womens-march-madness-bracket/">Women’s March Madness Futures Odds</a></li>
<li><a href="/articles/ncaab/march-madness-final-four/" target="_self" rel="noopener">2024 Men’s Final Four Odds</a></li>
<li><a href="/articles/ncaab/march-madness-sleepers/" target="_self" rel="noopener">Six Men’s March Madness Sleepers for 2024</a></li>
<li><a href="/guides/march-madness/" target="_self" rel="noopener">Best March Madness Betting Tips &amp; Strategies</a></li>
<li><a href="/articles/ncaab/march-madness-picks/" target="_self" rel="noopener">Where to Find the Best March Madness Betting Picks</a></li>
<li><a href="/march-madness/best-march-madness-betting-sites/" target="_self" rel="noopener">Best March Madness Betting Sites for This Year</a></li>
<li><a href="/march-madness/best-march-madness-bracket-challenges/" target="_self" rel="noopener">This Year’s Best March Madness Bracket Challenges</a></li>
<li><a href="https://fantasy.espn.com/games/tournament-challenge-bracket-2024/group?id=075a2d25-928f-4ec2-951d-313ceb792aac&amp;joinKey=ff4b668b-a1e0-3dd2-a24f-18a6a1d481f2&amp;joining=true" target="_self" rel="noopener">Betting News Bracket Mania</a> (Our FREE March Madness Bracket Challenge!)</li>
</ul>
<h3>Interested in Learning More About Betting on March Madness &amp; NCAA Basketball?</h3>
<p>If you are interested in learning more about betting on men’s or women’s NCAA basketball, check out our college basketball betting guide. It covers the basics of wagering on March Madness, the Mountain West, the MAAC, McNeese State, and beyond.</p>
<ul>
<li><a href="/guides/college-basketball-betting-guide/">College Basketball Betting Guide: How to Bet on NCAA Basketball in 2024</a></li>
</ul>
<p>Also, follow Betting News on X/Twitter, Twitch, and TikTok to get more March Madness and NCAA basketball insight from myself and the rest of our team. We’re cooking up a lot of great NCAA Tournament content for both the men’s and women’s tournaments, so hit those links so you don’t miss out on any of it.</p>
<ul>
<li><a href="https://twitter.com/YourBettingNews">Betting News on “X”/Twitter</a></li>
<li><a href="https://www.twitch.tv/bettingnews">Betting News on Twitch</a></li>
<li><a href="https://www.tiktok.com/@yourbettingnews?lang=en">Betting News on TikTok</a></li>
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