CBS Sports

Dratings

DunkelIndex

GameSim

OddsShark

Sports Betting Dime

Moneyline

Total

Point Spread

Away/Home

Wins

Ov / Un

Giants

Joey Bart

Curt Casali

Michael Papierski

Austin Wynns

Yermín Mercedes

Andrew Knapp

Thairo Estrada

Mauricio Dubón

Joc Pederson

Darin Ruf

Brandon Crawford

Wilmer Flores

Tommy La Stella

Evan Longoria

Brandon Belt

Jason Vosler

Luke Williams

Mike Ford

Kevin Padlo

Donovan Walton

David Villar

Dixon Machado

J.D. Davis

Ford Proctor

Jaylin Davis

Steven Duggar

Heliot Ramos

Austin Dean

LaMonte Wade Jr

Mike Yastrzemski

Austin Slater

Luis González

Ka'ai Tom

Jason Krizan

Stuart Fairchild

Bryce Johnson

Lewis Brinson

Willie Calhoun

Yunior Marte

Alex Cobb

John Brebbia

Randy Rodriguez

Tyler Beede

Logan Webb

Jarlin García

Gregory Santos

José Álvarez

Anthony DeSclafani

Jake McGee

Kervin Castro

Sean Hjelle

Alex Wood

Tyler Rogers

Zack Littell

Camilo Doval

Jakob Junis

Dominic Leone

Sam Long

Matthew Boyd

Carlos Rodón

Mauricio Llovera

Alex Young

Thomas Szapucki

Scott Alexander

Luis Ortiz

Cole Waites

Jharel Cotton

Shelby Miller

Andrew Vasquez

Cardinals

Ali Sánchez

Andrew Knizner

Yadier Molina

Iván Herrera

Austin Romine

Nolan Arenado

Edmundo Sosa

Paul DeJong

Paul Goldschmidt

Tommy Edman

Brendan Donovan

Juan Yepez

Albert Pujols

Kramer Robertson

Nolan Gorman

Cory Spangenberg

Alec Burleson

Dylan Carlson

Lars Nootbaar

Tyler O'Neill

Harrison Bader

Corey Dickerson

Conner Capel

Ben DeLuzio

Steven Matz

Angel Rondón

Alex Reyes

Miles Mikolas

T.J. McFarland

Nick Wittgren

Johan Quezada

Brandon Waddell

Giovanny Gallegos

Dakota Hudson

T.J. Zeuch

Jack Flaherty

Kodi Whitley

Jake Walsh

Adam Wainwright

Johan Oviedo

Ryan Helsley

Jake Woodford

Freddy Pacheco

Drew VerHagen

Jordan Hicks

Génesis Cabrera

Junior Fernández

Packy Naughton

Aaron Brooks

Andre Pallante

Matthew Liberatore

Zack Thompson

James Naile

Jose Quintana

Chris Stratton

Jordan Montgomery

JoJo Romero

Away/Home Defense

Away/Home Offense

Defense

Offense

San Francisco Giants vs St. Louis Cardinals Picks

Busch Stadium

<p>The current series and season series between the St. Louis Cardinals and San Francisco Giants is all nodded up. The Cardinals are coming off of a 4-0 shutout win on Saturday night which ended the Giants’ 6 game win streak.</p>
<p>Cardinals’ pitcher, Dakota Hudson, held the Giants to five hits in his 5 innings of work. He was only able to strike out two batters, but held San Francisco at bay for his third victory of the season.</p>
<p>With the shutout win, St. Louis has now recorded 6 shutouts this season. They only trail the Los Angeles Angels in that department.</p>
<p>Today’s game will feature two more pitchers with the ability to limit runs and strike out a dozen. Both teams are in the Top 10 in ERA this season. The two men who will take the hill this evening are a big part in that.</p>
<p>Carlos Rodón and Adam Wainwright have both seen success on the mound. They both have sub-4.00 ERAs and have limited walks. They are walking less than 3 batters for every 9 innings pitched. Having less runners on base has lowered each pitcher’s ERA and WHIP to elite levels.</p>
<h2 id="94uim">San Francisco Giants vs. St. Louis Cardinals May 15 Betting Odds and Matchup Information</h2>
<h3 id="b1hua">Matchup Information</h3>
<ul>
<li>Matchup: San Francisco Giants (20-13, 9-6 on the road, 3rd in the NL West) vs. St. Louis Cardinals (18-15, 9-8 at home, 2nd in the NL Central)</li>
<li>Venue &amp; Location: Busch Stadium (St. Louis, Missouri)</li>
<li>Date: Sunday, May 15, 2022</li>
<li>Time: 7:08 p.m. Eastern Time (6:08 p.m. local time)</li>
<li>How to Watch Today’s Giants vs. Cardinals Game: ESPN</li>
</ul>
<h3 id="8noso">Giants vs. Cardinals Probable Starting Pitching Matchup for Today</h3>
<ul>
<li>San Francisco Giants: Carlos Rodón (2022: 6 starts, 4-1, 1.80 ERA)</li>
<li>St. Louis Cardinals: Adam Wainwright (2022: 6 starts, 3-3, 3.18 ERA)</li>
</ul>
<h3 id="dnfqb">Giants vs. Cardinals Odds</h3>
<p><strong><em>Odds are via <a href="https://affiliates.bettingnews.com/register/betonline/">BetOnline</a>.</em></strong></p>
<h4 id="d8ceg">Moneyline</h4>
<ul>
<li>San Francisco Giants -146</li>
<li>St. Louis Cardinals +124</li>
</ul>
<h4 id="7io6e">Over/Under</h4>
<ul>
<li>OVER 7 (-115)</li>
<li>UNDER 7 (-105)</li>
</ul>
<h4 id="c9ran">Run Line</h4>
<ul>
<li>San Francisco Giants -1.5 (+126)</li>
<li>St. Louis Cardinals +1.5 (-152)</li>
</ul>
<h2 id="cgqev">Carlos Rodón’s Hot Start</h2>
<p>Rodón has had a Cy Young caliber start to the 2022 campaign. Hee has an ERA under 2.00 and is striking out nearly 9 batters per start. He has 8 or more strikeouts in 5 of his first 6 starts.</p>
<p>In his last start against Colorado, he managed to whiff 12 batters and pick up his fourth win of the season. It was his sixth straight start of 5 innings or more to start the season.</p>
<p>Rodón has only allowed 7 runs to cross the plate in his time with the club this season. He has not given up a home run this year and his WHIP is under 1.00.</p>
<p>His hot start could get an even bigger boost on Sunday night if he can put together his 7th straight solid outing to start the season. His stuff is on point and he can strikeout the best of them when he is on his game.</p>
<h2 id="9f29t">San Francisco Giants vs. St. Louis Cardinals May 15 Prediction and Best Bets</h2>
<p><strong>Giants vs. Cardinals Prediction:</strong> Giants 4, Cardinals 2</p>
<p><strong>Giants vs. Cardinals Best Bets: </strong>Giants -1.5 (+126 at <a href="https://sportsbook.fanduel.com/baseball/mlb/san-francisco-giants-@-st.-louis-cardinals-31456992">BetOnline</a>)</p>
<p>Although the Cardinals were able to put up a shutout win last night, I don’t see a repeat of that tonight. With the Giants sending Rodón to the hill, the Cardinals will have a harder time making solid contact and getting the ball into the outfield.</p>
<p>The Giants’ offense has had a history of putting up big numbers against St. Louis this season. 8 days ago they played this Cardinals team and scored 13 runs. The bats have exploded and they hold a good record on the road.</p>
<p>With solid pitching expected tonight, don’t expect 13 runs to be put up on the scoreboard. Lots of strikeouts and ground balls will make it difficult for the Cardinals to get on base early. For the Giants, they need to jump on Wainwright early to put pressure on the savvy veteran. </p>
<p><script>if(window.strchfSettings === undefined) window.strchfSettings = {};window.strchfSettings.stats = {url: "https://betting-news.storychief.io/en/giants-vs-cardinals-odds-best-bets-2022-may15?id=1496576040&type=2",title: "Giants vs. Cardinals Odds and Best Bets for May 15: Solid Pitching to Lead Giants to Series Win",id: "4af471aa-0a59-40f0-a023-eeb51e59464b"};(function(d, s, id) {var js, sjs = d.getElementsByTagName(s)[0];if (d.getElementById(id)) {window.strchf.update(); return;}js = d.createElement(s); js.id = id;js.src = "https://d37oebn0w9ir6a.cloudfront.net/scripts/v0/strchf.js";js.async = true;sjs.parentNode.insertBefore(js, sjs);}(document, 'script', 'storychief-jssdk'))</script></p>

Giants vs. Cardinals Odds and Best Bets for May 15: Solid Pitching to Lead Giants to Series Win

MLB Signs Streaming Deals with Netflix, ESPN & NBCUniversal

2026 World Series: Too Early Odds | November 2, 2025

Dodgers vs. Blue Jays: Game 7 Player Props | November 1, 2025

Blue Jays vs. Dodgers: Game 7 Odds & Props | November 1, 2025

Yamamoto is Top 10 in both ERA and WHIP this season - Dodgers Brewers Picks & Predictions

2025 World Series Props Odds Update | October 31, 2025