<p>After a slow start this season, the Seattle Mariners now sit atop of the AL West. Key to that rise in the standings has been success in close games. Their latest tight triumph has them poised to break out the brooms against the Houston Astros this afternoon (4:10 pm ET, ESPN+).</p>
<p>The first three games of the series between Houston (24-32) and Seattle (31-26) have been close, low-scoring contests. After winning 3-2 on Monday and 4-2 on Tuesday, the Mariners walked it off with a 2-1 win in Wednesday’s matchup, with J.P. Crawford’s sac fly in the 10<sup>th</sup> plating the decisive run.</p>
<p>Will Houston be able to salvage something from this series before heading home to host the Minnesota Twins? Or will Seattle pick up a season-high fifth straight win?</p>
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<h2>Houston Astros vs Seattle Mariners Odds</h2>
<p><strong><em>Odds are via <a href="https://affiliates.bettingnews.com/register/betonline/" target="_blank" rel="noopener sponsored">BetOnline</a>, a longtime fixture in the sports betting industry. Check out our <a href="/best-online-sportsbooks/betonline/" target="_blank" rel="noopener sponsored">BetOnline sportsbook review</a>, then grab yourself a nice sign-up bonus to bet on Major League Baseball.</em></strong></p>
<h3>Moneyline</h3>
<ul>
<li>Houston Astros +128</li>
<li>Seattle Mariners -139</li>
</ul>
<h3>Over/Under</h3>
<ul>
<li>Over 7.5 (-108)</li>
<li>Under 7.5 (-112)</li>
</ul>
<h3>Run Line</h3>
<ul>
<li>Houston Astros +1.5 (-175)</li>
<li>Seattle Mariners -1.5 (+155)</li>
</ul>
<p><strong><em>Looking for more baseball picks? Our <a href="/mlb/picks/">MLB picks</a> page features moneyline, total (over/under), and run line (spread) picks for every MLB game on the schedule each day.</em></strong></p>
<h2>Pitching Matchup for Astros vs Mariners</h2>
<ul>
<li>Houston Astros: RHP Spencer Arrighetti (8 starts, 2-5, 6.93 ERA)</li>
<li>Seattle Mariners: RHP Logan Gilbert (11 starts, 3-2, 3.06 ERA)</li>
</ul>
<h2>Houston Astros vs Seattle Mariners Betting Analysis</h2>
<p>After facing and being stymied by Bryce Miller (6 IP, 5 H, 2 R, 2 BB, 6 K), Luis Castillo (6 IP, 5 H, 2 R, BB, 6 K), and George Kirby (6 IP, 6 H, R, 0 BB, 8 K), the Astros must deal with Gilbert in the series finale.</p>
<p>When they last did so, the 27-year-old tossed eight shutout innings, allowed two hits and four walks, and struck out six in a 5-0 Mariners win in Houston on May 4.</p>
<p>Gilbert’s ERA is inflated somewhat by his next start, in which he allowed eight runs in four innings at Minnesota. That was a rough result, but he has been one of the standout starters in MLB over the first two months of the season. He has gone 6+ innings and allowed three or fewer runs nine times, including each of his four home starts.</p>
<p>His opposite number has had some nice outings this season, but none of them have been away from the comfort of Minute Maid Park. Arrighetti has a 10.26 ERA in his four road starts, and he has given up 27 hits, 19 runs (all earned), and 11 walks in just 16.2 innings. Unsurprisingly, the Astros have lost all four of those games.</p>
<p>The outlook isn’t an optimistic one here, either. The Mariners have a major advantage on the mound and are just better overall right now. Take the home to break out the brooms and put some runs on the board against Arrighetti in the process after scoring nine runs in the first three games.</p>
<h2>Houston Astros vs Seattle Mariners Prediction &amp; Best Bets</h2>
<p><strong>Astros vs Mariners Prediction:</strong> Mariners to win</p>
<p><strong>Astros vs Mariners Best Bets:</strong> 1) Mariners ML, 2) Mariners -1.5, 3) Mariners team total over 3.5 runs (-135 at Bovada), 4) Logan Gilbert over 5.5 strikeouts (+105 at Bovada)</p>
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<h2>More MLB Betting Information</h2>
<h3>How to Bet on Major League Baseball in 2024</h3>
<p>There are many ways to bet on Major League Baseball. As with the NFL, NBA, and NHL, the main ways are moneyline and spread betting, as well as over/under betting.</p>
<p><a href="/guides/futures-bets/">Futures bets</a> (like Cy Young odds) and <a href="/guides/understanding-prop-bets/">prop bets</a> (like strikeout props and batting props) are also one of the most popular ways to bet on the action on the diamond.</p>
<h3>Where to Bet on MLB</h3>
<p>Many top <a href="/best-online-sportsbooks/">online sportsbooks</a> offer a wide variety of <a href="/mlb/odds/">MLB odds</a> throughout the season.</p>
<p>In addition to being able to make <a href="/mlb/picks/">daily MLB picks</a> on games from Opening Day until the final game of the Fall Classic, you can also bet on <a href="/articles/mlb/mlb-mvp-odds/">MLB MVP odds</a>, <a href="/articles/mlb/cy-young-award-odds/">Cy Young Award odds</a>, and <a href="/articles/mlb/mlb-rookie-of-the-year-odds/">MLB Rookie of the Year odds</a>, as well as World Series odds.</p>
<p>There are many sportsbooks out there that are good for betting on baseball, but here are some of the books that we have reviewed and highly recommend:</p>
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<li><a href="/best-online-sportsbooks/betdsi/" target="_blank" rel="noopener sponsored">BetDSI (Review)</a></li>
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<li><a href="/best-online-sportsbooks/betus/" target="_blank" rel="noopener sponsored">BetUS (Review)</a></li>
<li><a href="/best-online-sportsbooks/bovada/" target="_blank" rel="noopener sponsored">Bovada (Review)</a></li>
<li><a href="/best-online-sportsbooks/everygame/" target="_blank" rel="noopener sponsored">Everygame (Review)</a></li>
<li><a href="https://affiliates.bettingnews.com/register/mybookie/" target="_blank" rel="noopener sponsored">MyBookie (Review)</a></li>
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<p>If you don’t have an account at a book on this list, check out our reviews to help you determine if it is worth your interest and your betting funds.</p>
<h3>Interested in Learning More About Betting on Baseball?</h3>
<p>Are you new to baseball betting or want to get more acquainted with some of the ins and outs of placing MLB bets, check out our MLB betting guide.</p>
<ul>
<li><a href="https://bettingnews.com/guides/mlb-betting-guide/">MLB Betting Guide: How to Bet on Baseball in 2024</a></li>
</ul>
<p>Did you enjoy this Astros vs Mariners betting breakdown? Bookmark Betting News so you don’t miss any of our daily MLB content. Also, check out our MLB picks and insights and other social content on X (formerly known as Twitter), Twitch, and TikTok.</p>
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