CBS Sports

Dratings

DunkelIndex

GameSim

OddsShark

Sports Betting Dime

Away/Home

Wins

Ov / Un

Padres

Luis Campusano

Victor Caratini

Austin Nola

Jorge Alfaro

Brett Sullivan

Eguy Rosario

Manny Machado

Jake Cronenworth

Ha-Seong Kim

Eric Hosmer

Luke Voit

Matt Beaty

CJ Abrams

Sergio Alcántara

Robinson Canó

Matthew Batten

Brandon Drury

Josh Bell

Brandon Dixon

Jurickson Profar

Efrain Contreras

Wil Myers

Fernando Tatis Jr.

Trent Grisham

Brent Rooker

Jose Azocar

Trayce Thompson

Nomar Mazara

Esteury Ruiz

Braedon Karpathios

Juan Soto

Luis Liberato

Javy Guerra

Nabil Crismatt

Robert Suarez

Steven Wilson

Pierce Johnson

Reiss Knehr

Emilio Pagán

Joe Musgrove

Craig Stammen

Austin Adams

Pedro Avila

Adrian Martinez

Drew Pomeranz

Yu Darvish

James Norwood

Dinelson Lamet

Ryan Weathers

Tim Hill

Adrian Morejon

MacKenzie Gore

Mike Clevinger

Ray Kerr

Blake Snell

Chris Paddack

Luis García

Michel Baez

Nick Martinez

Kyle Tyler

Sean Manaea

Taylor Rogers

Tayler Scott

Josh Hader

José Castillo

Brewers

Pedro Severino

Mario Feliciano

Omar Narváez

Alex Jackson

Alex Hall

Luis Urías

Keston Hiura

Kolten Wong

Jace Peterson

Rowdy Tellez

Mike Brosseau

Willy Adames

Mark Mathias

Tyrone Taylor

Pablo Reyes

Christian Yelich

Hunter Renfroe

Corey Ray

Lorenzo Cain

Andrew McCutchen

Jonathan Davis

Garrett Mitchell

Miguel Sanchez

Hoby Milner

Justin Topa

Dylan File

Angel Perdomo

Jandel Gustave

Eric Lauer

Devin Williams

Corbin Burnes

Aaron Ashby

Freddy Peralta

Jake Cousins

Brandon Woodruff

Brad Boxberger

Adrian Houser

Trevor Gott

Brent Suter

Alec Bettinger

J.C. Mejia

José Ureña

Luis Perdomo

Trevor Kelley

Ethan Small

Peter Strzelecki

Luke Barker

Jason Alexander

Chi Chi González

Connor Sadzeck

Jake McGee

Matt Bush

Away/Home Defense

Away/Home Offense

Defense

Offense

San Diego Padres vs Milwaukee Brewers Picks

American Family Field

<p>Two of baseball’s top pitchers will duel tonight in Milwaukee as Joe Musgrove and the San Diego Padres visit Corbin Burnes and the Brewers.</p>
<p>Burnes is the reigning NL <a href="/articles/mlb/cy-young-award-odds/" target="_blank" rel="noopener noreferrer">Cy Young Award</a> winner and is favored to become a repeat winner, coming in at +350 at BetOnline entering today. Musgrove, meanwhile, comes in with +950 odds, placing him third behind Burnes and Miami Marlins hurler Sandy Alcantara.</p>
<p>This will be Musgrove’s first outing against the Brewers this season, but Burnes has already shut down the Padres once this season in San Diego. Will he do it again tonight at American Family Field?</p>
<h2 id="4s6l9">San Diego Padres vs. Milwaukee Brewers Betting Odds and Matchup Information</h2>
<h3 id="eevcn">Matchup Information</h3>
<ul>
<li>Matchup: San Diego Padres (30-21, 17-11 road, 2nd in the NL West) vs. Milwaukee Brewers (33-20, 15-6 home, 1st in the NL Central</li>
<li>Venue &amp; Location: American Family Field (Milwaukee, Wisconsin)</li>
<li>Date: Friday, June 3, 2022</li>
<li>Time: 8:10 p.m. Eastern Time (7:10 p.m. local time)</li>
<li>How to Watch Today’s Padres vs. Brewers Game: Bally Sports San Diego (Padres), Bally Sports Wisconsin (Brewers), MLB Extra Innings (subscription package)</li>
</ul>
<h3 id="3dpl6">Padres vs. Brewers Pitching Matchup</h3>
<ul>
<li>San Diego Padres: Joe Musgrove (2022: 9 starts, 5-0, 1.86 ERA)</li>
<li>Milwaukee Brewers: Corbin Burnes (2022: 10 starts, 3-2, 1.95 ERA)</li>
</ul>
<h3 id="6ic9g">Padres vs. Brewers Odds</h3>
<p><strong><em>Game odds are via <a href="https://affiliates.bettingnews.com/register/betonline/" target="_blank" rel="noopener noreferrer">BetOnline</a>. Odds from our other top reviewed and recommended <a href="/best-online-sportsbooks/">sportsbooks</a> may also be included in this article.</em></strong></p>
<h4 id="3t4au">Moneyline</h4>
<ul>
<li>San Diego Padres +138</li>
<li>Milwaukee Brewers -164</li>
</ul>
<h4 id="48aql">Over/Under</h4>
<ul>
<li>OVER 6.5 (-122)</li>
<li>UNDER 6.5 (+100)</li>
</ul>
<h4 id="ejmma">Run Line</h4>
<ul>
<li>San Diego Padres +1.5 (-172)</li>
<li>Milwaukee Brewers -1.5 (+142)</li>
</ul>
<h2 id="6kem9">Will Burnes Shut Down San Diego for the Second Time in Short Order?</h2>
<p>Luck&#8211;and run support&#8211;have not been on Burnes’s side multiple times this season, but they were when he faced the Padres in San Diego ten days ago.</p>
<p>In that outing on May 24, he allowed only one run, five hits, and two walks and struck out five in six innings, and the Brewers did their part at the plate to produce a 4-1 win. </p>
<p>Things went his and Milwaukee’s way again in his most recent start this past Sunday in St. Louis. He tossed seven shutout innings, allowed only two hits and a walk, and struck out a season-high-tying 11 in an 8-0 win over the rival Cardinals.</p>
<p>After recording 18 quality starts in 28 overall starts in his Cy Young-winning campaign last year, Burnes has eight quality starts in his ten starts thus far this season. </p>
<p>Burnes has been better on the road than at home, but he has been much better in night games than day games, so those splits work out favorably for tonight’s matchup. In night games, he is 2-1 with a 1.13 ERA in six starts, while he is 1-1 with a 3.24 ERA in four daytime starts. </p>
<p>Musgrove, meanwhile, is marginally better at home and in day games, though given that all of his splits are pretty darn good, that is more or less splitting hairs.</p>
<h3 id="bpgeu">Season Splits for Joe Musgrove</h3>
<ul>
<li>Home: 4 starts, 2-0, 1.73 ERA</li>
<li>Away: 5 starts, 3-0, 1.97 ERA</li>
<li>Day: 4 starts, 2-0, 1.67 ERA</li>
<li>Night: 5 starts, 3-0, 2.03 ERA</li>
</ul>
<h2 id="5fa3o">San Diego Padres vs. Milwaukee Brewers Prediction and Best Bets</h2>
<p><strong>Padres vs. Brewers Prediction:</strong> Brewers to win</p>
<p><strong>Padres vs. Brewers Best Bets:</strong> Brewers ML (-155 at <a href="https://affiliates.bettingnews.com/register/bmgm/" target="_blank" rel="noopener noreferrer">BetMGM</a>) &amp; UNDER 6.5 (+100 at <a href="https://affiliates.bettingnews.com/register/betonline/" target="_blank" rel="noopener noreferrer">BetOnline</a>, <a href="https://affiliates.bettingnews.com/register/bovada/" target="_blank" rel="noopener noreferrer">Bovada Sportsbook</a>, <a href="https://affiliates.bettingnews.com/register/mybookie/" target="_blank" rel="noopener noreferrer">MyBookie</a> &amp; BetMGM)</p>
<p>The Padres have gone cold at the plate and in the win column as of late, though they did actually manage four runs in yesterday’s series-opening 5-4 loss.</p>
<p>The loss was San Diego’s seventh in nine games, and it marked only the third time in ten games that the Padres managed to score four or more runs.</p>
<p>One of those ten games was Burnes’s start in San Diego, and the odds are not particularly favorable that they will fare much better tonight.</p>
<p>The Brewers have been more prolific and productive at the plate at home than on the road, averaging 5.29 runs per game at home (sixth in MLB) and scoring 5+ runs 13 times in 21 home games this season. </p>
<p>Musgrove shouldn’t give too much away, but he will give enough away to tip the scales in Milwaukee’s favor tonight, thanks to Burnes shutting down the Padres for the second time in less than two weeks.</p>
<p>Last night’s game was a one-run win for the Brewers, but there is some value in backing the Brewers to win by multiple runs tonight. Of their 15 home wins this season, 11 have come by 2+ runs, and they have won back-to-back games by one run only once thus far in 2022. </p>
<p>If you want to back the -1.5 run line, the best value can be found at <a href="/best-online-sportsbooks/betonline/" target="_blank" rel="noopener noreferrer">BetMGM</a>, where Brewers -1.5 is +145 at the time of writing.</p>
<p><script>if(window.strchfSettings === undefined) window.strchfSettings = {};window.strchfSettings.stats = {url: "https://betting-news.storychief.io/en/padres-vs-brewers-prediction-best-bets-june-3-2022?id=1342974830&type=2",title: "Padres vs. Brewers (June 3): Back Burnes to stymie San Diego yet again",id: "4af471aa-0a59-40f0-a023-eeb51e59464b"};(function(d, s, id) {var js, sjs = d.getElementsByTagName(s)[0];if (d.getElementById(id)) {window.strchf.update(); return;}js = d.createElement(s); js.id = id;js.src = "https://d37oebn0w9ir6a.cloudfront.net/scripts/v0/strchf.js";js.async = true;sjs.parentNode.insertBefore(js, sjs);}(document, 'script', 'storychief-jssdk'))</script></p>

Padres vs. Brewers (June 3): Back Burnes to stymie San Diego yet again

Eddie Griffin

More MLB News

2026 World Series Odds & More: The Pete Alonso Effect | December 11, 2025

MLB Signs Streaming Deals with Netflix, ESPN & NBCUniversal

2026 World Series: Too Early Odds | November 2, 2025

Dodgers vs. Blue Jays: Game 7 Player Props | November 1, 2025

Blue Jays vs. Dodgers: Game 7 Odds & Props | November 1, 2025