CBS Sports

Dratings

DunkelIndex

GameSim

OddsShark

Sports Betting Dime

Moneyline

Total

Point Spread

Away/Home

Wins

Ov / Un

Guardians

Austin Hedges

Bryan Lavastida

Luke Maile

Sandy León

Bo Naylor

Josh Naylor

Yu Chang

Amed Rosario

Ernie Clement

Andrés Giménez

Brayan Rocchio

Jose Tena

Gabriel Arias

José Ramírez

Owen Miller

Bobby Bradley

George Valera

Richie Palacios

Jhonkensy Noel

Tyler Freeman

Nolan Jones

Steven Kwan

Myles Straw

Oscar Mercado

Bradley Zimmer

Franmil Reyes

Oscar Gonzalez

Alex Call

Will Benson

Will Brennan

Shane Bieber

Eli Morgan

James Karinchak

Nick Sandlin

Cody Morris

Konnor Pilkington

Tobias Myers

Triston McKenzie

Logan Allen

Emmanuel Clase

Cal Quantrill

Aaron Civale

Sam Hentges

Trevor Stephan

Zach Plesac

Anthony Gose

Bryan Shaw

Anthony Castro

Tanner Tully

Enyel De Los Santos

Kirk McCarty

Yohan Ramírez

Ian Gibaut

Alex Young

Hunter Gaddis

Jake Jewell

Peyton Battenfield

Xzavion Curry

Carlos Vargas

Tigers

Tucker Barnhart

Jake Rogers

Dustin Garneau

Eric Haase

Isaac Paredes

Kody Clemens

Jonathan Schoop

Harold Castro

Zack Short

Jeimer Candelario

Miguel Cabrera

Spencer Torkelson

Ryan Kreidler

Josh Lester

Javier Báez

Victor Reyes

Willi Castro

Akil Baddoo

Daz Cameron

Robbie Grossman

Derek Hill

Austin Meadows

Riley Greene

Kerry Carpenter

Brendon Davis

Eduardo Rodriguez

Tarik Skubal

Casey Mize

Tyler Alexander

Gregory Soto

Andrew Chafin

Spencer Turnbull

Jason Foley

Miguel Del Pozo

Angel De Jesus

Elvin Rodriguez

Rony García

Matt Manning

Joey Wentz

Michael Fulmer

Joe Jiménez

Kyle Funkhouser

José Cisnero

Bryan Garcia

Alex Lange

Alex Faedo

Michael Pineda

Drew Hutchison

Jacob Barnes

Will Vest

Wily Peralta

Beau Brieske

Drew Carlton

Garrett Hill

Derek Law

Luis Castillo

Daniel Norris

Miguel Diaz

Away/Home Defense

Away/Home Offense

Defense

Offense

Cleveland Guardians vs Detroit Tigers Picks

Comerica Park

<p>Wednesday’s MLB schedule opens in Detroit, where the Tigers will be looking to wrap up a four-game sweep of the slip-sliding Cleveland Guardians.</p>
<p>After winning a doubleheader on Monday, the Tigers wrapped up the series win yesterday with a resounding 11-4 win. In the win, Detroit recorded 13 hits on the way to scoring 10+ runs for just the third time this season.</p>
<p>In this afternoon’s finale, the Guardians will be looking for more from their bats while also looking for Shane Bieber to continue his recent run of positive performances.</p>
<h2 id="enhmd">Cleveland Guardians vs. Detroit Tigers Betting Odds and Matchup Information</h2>
<h3 id="9qg43">Matchup Information</h3>
<ul>
<li>Matchup: Cleveland Guardians (40-39, 20-22 away, 2nd in the AL Central) vs. Detroit Tigers (33-47, 22-24 home, 4th in the AL Central)</li>
<li>Venue &amp; Location: Comerica Park (Detroit, Michigan)</li>
<li>Date: Wednesday, July 6, 2022</li>
<li>Game Time: 1:10 p.m. Eastern Time</li>
<li>TV Broadcast/Streaming Info: MLB Network</li>
</ul>
<h3 id="ef5d4">Guardians vs. Tigers Pitching Matchup</h3>
<ul>
<li>Cleveland Guardians: Shane Bieber (2022: 15 starts, 3-4, 3.16 ERA)</li>
<li>Detroit Tigers: Michael Pineda (2022: 6 starts, 1-3, 3.62 ERA)</li>
</ul>
<h3 id="3uo0v">Guardians vs. Tigers Odds</h3>
<p><strong><em>Game odds are via <a href="https://affiliates.bettingnews.com/register/betonline/" target="_blank" rel="noopener noreferrer">BetOnline</a>. This article may also include odds from other <a href="/best-online-sportsbooks/" target="_blank" rel="noopener noreferrer">top online sportsbooks</a> that we have reviewed and recommend.</em></strong></p>
<h4 id="3ln5i">Moneyline</h4>
<ul>
<li>Cleveland Guardians -180</li>
<li>Detroit Tigers +152</li>
</ul>
<h4 id="7pr1o">Over/Under</h4>
<ul>
<li>OVER 7.5 (-105)</li>
<li>UNDER 7.5 (-115)</li>
</ul>
<h4 id="fn1si">Run Line</h4>
<ul>
<li>Cleveland Guardians -1.5 (+100)</li>
<li>Detroit Tigers +1.5 (-120)</li>
</ul>
<h2 id="3d8bl">Will Bieber Remain a Bright Spot Amidst Cleveland’s Current Struggles?</h2>
<p>Two weeks ago, the Guardians briefly moved into first place in the AL Central thanks to a hot streak that spanned the end of May and the first three weeks of June.</p>
<p>But that streak is all but a distant memory at this point, as Cleveland has now lost 11 of 15 games. After following a five-game losing streak by winning three of the final four games of their five-game series against the Minnesota Twins last week, last night’s loss made it five losses in their last six games.</p>
<p>Bieber certainly did his part during Cleveland’s hot streak and will look to continue his current run of form in his first start of July. </p>
<p>Last Thursday, Bieber posted his eighth quality start in his last nine starts, as he allowed three runs, five hits, and two walks in the Guardians’ series-clinching win over the Twins. He only has two wins in the period, but Cleveland is sporting a robust 7-2 record in these last nine starts. </p>
<p>Two of those starts came against the Tigers, including a season-best outing in his last visit to Detroit on May 28. In that start, he went a season-high eight innings, allowed eight hits and no walks, and struck out five in Cleveland’s 8-1 win.</p>
<p>Another strong start is likely today, based on how much success he has had on the road in his career and how much he loves pitching at Comerica Park.</p>
<h3 id="8ftg0">Notable Splits for Shane Bieber</h3>
<ul>
<li>Away (career): 53 appearances (52 starts), 28-9, 2.78 ERA, 1.01 WHIP</li>
<li>Away (2022): 9 starts, 2-1, 2.51 ERA, 1.13 WHIP</li>
<li>At Comerica Park (career): 7 starts, 6-1, 1.79 ERA, 0.80 WHIP</li>
</ul>
<p>If the Guardians can score four runs today, it will likely net a better result than last night’s output did. They have scored 3+ runs in seven of Bieber’s nine road starts, and they have won all seven of those games.</p>
<h2 id="2df3i">Cleveland Guardians vs. Detroit Tigers Prediction and Best Bets</h2>
<p><strong>Guardians vs. Tigers Prediction:</strong> Guardians to win</p>
<p><strong>Guardians vs. Tigers Best Bets:</strong> Guardians -1.5 (+105 at <a href="https://affiliates.bettingnews.com/register/bovada/" target="_blank" rel="noopener noreferrer">Bovada Sportsbook</a> &amp; <a href="https://affiliates.bettingnews.com/register/mybookie/" target="_blank" rel="noopener noreferrer">MyBookie</a>)</p>
<p>Look for the Guardians to come away with a consolation win this afternoon at Comerica Park, with another quality start from Bieber&#8211;his eighth in a row on the road&#8211;leading the way. </p>
<p>Of the 10 wins that Cleveland has in Bieber’s starts this season, eight have come by 2+ runs, including five of the seven road starts they have won. </p>
<p>Backing the run line may feel risky given the form that the Guardians are in at the moment, sure. After all, they have been held to three or fewer runs 11 times in their last 15 games. But if Bieber continues his success against Detroit in Detroit, Cleveland won’t need to have a big game at the plate to get this one to cash.</p>
<p><script>if(window.strchfSettings === undefined) window.strchfSettings = {};window.strchfSettings.stats = {url: "https://betting-news.storychief.io/en/guardians-vs-tigers-prediction-best-bets-july-6-2022?id=593489321&type=2",title: "Guardians vs. Tigers (July 6): Can Bieber stop Cleveland’s skid by dominating Detroit again?",id: "4af471aa-0a59-40f0-a023-eeb51e59464b"};(function(d, s, id) {var js, sjs = d.getElementsByTagName(s)[0];if (d.getElementById(id)) {window.strchf.update(); return;}js = d.createElement(s); js.id = id;js.src = "https://d37oebn0w9ir6a.cloudfront.net/scripts/v0/strchf.js";js.async = true;sjs.parentNode.insertBefore(js, sjs);}(document, 'script', 'storychief-jssdk'))</script></p>

Guardians vs. Tigers (July 6): Can Bieber stop Cleveland’s skid by dominating Detroit again? cover

Guardians vs. Tigers (July 6): Can Bieber stop Cleveland’s skid by dominating Detroit again?

Guardians vs. Tigers (July 6): Can Bieber stop Cleveland’s skid by dominating Detroit again?

Eddie Griffin

More MLB News

2026 World Series Odds & More: The Pete Alonso Effect | December 11, 2025

MLB Signs Streaming Deals with Netflix, ESPN & NBCUniversal

2026 World Series: Too Early Odds | November 2, 2025

Dodgers vs. Blue Jays: Game 7 Player Props | November 1, 2025

Blue Jays vs. Dodgers: Game 7 Odds & Props | November 1, 2025