Buffalo Bills

2021 Record: 0-0

After a couple of decades wandering in the wilderness after their success under Hall of Fame quarterback Jim Kelly and Hall of Fame coach Marv Levy, the Buffalo Bills are poised for big things behind quarterback Josh Allen and coach Sean McDermott. Last season, the Bills went 13-3 and won the AFC East for the first time since 1995. They hosted a playoff game for the first time since the 1996 season, won their first playoff game since the 1995 season, and advanced to the AFC Championship Game for the first time since the 1993 season.

Entering the 2021 season, the Bills are expected to build off of last season’s success and further establish themselves as the new power in the AFC East. NFL futures odds view the Bills as a strong favorite to win the AFC East for the second straight campaign, and they are also viewed as the second favorite in the AFC behind Patrick Mahomes and the Kansas City Chiefs, who defeated the Bills in last season’s AFC title game.

The future is as bright for the Bills as any team in the NFL. Will they take the next step in 2021?

Buffalo Bills 2021 Schedule

Times are subject to change. Game odds are via FanDuel Sportsbook and are updated as of Friday, August 13, 2021.

Week 1

Date, Matchup, Time, and TV Broadcast Information

Sunday, September 12, 2021: vs Pittsburgh Steelers, 1:00 pm ET, CBS

Pittsburgh Steelers vs Buffalo Bills Betting Odds

  • Spread: Pittsburgh Steelers +7 (-110), Buffalo Bills -7 (-110)
  • Total: OVER 50 (-110), UNDER 50 (-110)
  • Moneyline: Pittsburgh Steelers +265, Buffalo Bills -330

Week 2

Sunday, September 19, 2021: at Miami Dolphins, 1:00 pm ET, FOX

Week 3

Sunday, September 26, 2021: vs Washington Football Team, 1:00 pm ET, CBS

Week 4

Sunday, October 3, 2021: vs Houston Texans, 1:00 pm ET, CBS

Week 5

Sunday, October 10, 2021: at Kansas City Chiefs, 8:20 pm ET, NBC

Week 6

Monday, October 18, 2021: at Tennessee Titans, 8:15 pm ET, ESPN

Week 7

BYE WEEK

Week 8

Sunday, October 31, 2021: vs Miami Dolphins, 1:00 pm ET, CBS

Week 9

Sunday, November 7, 2021: at Jacksonville Jaguars, 1:00 pm ET, CBS

Week 10

Sunday, November 14, 2021: at New York Jets, 1:00 pm ET, CBS

Week 11

Sunday, November 21, 2021: vs Indianapolis Colts, 1:00 pm ET, CBS

Week 12

Thursday, November 25, 2021: at New Orleans Saints, 8:20 pm ET, NBC

Week 13

Monday, December 6, 2021: vs New England Patriots, 8:15 pm ET, ESPN

Week 14

Sunday, December 12, 2021: at Tampa Bay Buccaneers, 4:25 pm ET, CBS

Week 15

Sunday, December 19, 2021: vs Carolina Panthers, TBD

Week 16

Sunday, December 26, 2021: at New England Patriots, 1:00 pm ET, CBS

Week 17

Sunday, January 2, 2022: vs Atlanta Falcons, 1:00 pm ET, FOX

Week 18

Sunday, January 9, 2022: vs New York Jets, 1:00 pm ET, CBS

Buffalo Bills 2021 Betting Information

  • SU: 0-0-0 (0-0-0 home, 0-0-0 away)
  • ATS: 0-0-0 (0-0-0 home, 0-0-0 away)
  • O/U: 0-0-0 (0-0-0 home, 0-0-0 away)

Buffalo Bills 2021 Statistical Summary

Scoring

  • Scoring Offense: 0.0
  • Scoring Defense: 0.0

Total Yards Per Game

  • Offense: 0.0
  • Defense: 0.0

Passing Yards Per Game

  • Offense: 0.0
  • Defense: 0.0

Rushing Yards Per Game

  • Offense: 0.0
  • Defense: 0.0

Buffalo Bills 2021 Season Odds

Odds to Win Super Bowl LVI

  • August 13: +1200

Odds to Win the AFC Championship

  • August 13: +550

Odds to Win the AFC East Title

  • August 13: -150

Odds to Make the NFL Playoffs

  • August 13: YES -410, NO +300

Buffalo Bills 2021 Season Win Total

  • August 13: OVER 11 (+100), UNDER 11 (-120)

Buffalo Bills odds are via FanDuel Sportsbook and are updated as of Friday, August 13, 2021.

Eddie Griffin
Eddie Griffin

Eddie Griffin has been writing about and Betting on sports for over a decade. For more of his thoughts on sports and sports betting, you can follow him on Twitter.

Eddie Griffin has been writing about and Betting on sports for over a decade. For more of his thoughts on sports and sports betting, you can follow him on Twitter.